Explore
Validate
Learn
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MAB1740 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1740, RRID:AB_1678614
- Product name
- OPRK1 monoclonal antibody, clone 5E3
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against OPRK1.
- Isotype
- IgG
- Antibody clone number
- 5E3
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence.
Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal.
kappa opioid receptors in human microglia downregulate human immunodeficiency virus 1 expression.
kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system.
Edenberg HJ, Wang J, Tian H, Pochareddy S, Xuei X, Wetherill L, Goate A, Hinrichs T, Kuperman S, Nurnberger JI Jr, Schuckit M, Tischfield JA, Foroud T
Human molecular genetics 2008 Jun 15;17(12):1783-9
Human molecular genetics 2008 Jun 15;17(12):1783-9
Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal.
Simonin F, Valverde O, Smadja C, Slowe S, Kitchen I, Dierich A, Le Meur M, Roques BP, Maldonado R, Kieffer BL
The EMBO journal 1998 Feb 16;17(4):886-97
The EMBO journal 1998 Feb 16;17(4):886-97
kappa opioid receptors in human microglia downregulate human immunodeficiency virus 1 expression.
Chao CC, Gekker G, Hu S, Sheng WS, Shark KB, Bu DF, Archer S, Bidlack JM, Peterson PK
Proceedings of the National Academy of Sciences of the United States of America 1996 Jul 23;93(15):8051-6
Proceedings of the National Academy of Sciences of the United States of America 1996 Jul 23;93(15):8051-6
kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system.
Simonin F, Gavériaux-Ruff C, Befort K, Matthes H, Lannes B, Micheletti G, Mattéi MG, Charron G, Bloch B, Kieffer B
Proceedings of the National Academy of Sciences of the United States of America 1995 Jul 18;92(15):7006-10
Proceedings of the National Academy of Sciences of the United States of America 1995 Jul 18;92(15):7006-10
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of HEK 293T cells overexpressing human OPRK1, using OPRK1 monoclonal antibody, clone 5E3 (Cat # MAB1740) .
- Validation comment
- Immunofluorescence
