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Protein structure
LIAS
Lipoic acid synthetaseLAS
The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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| Proteintech Group |  11577-1-AP |
31 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | H00011019-M03 |
1 references | Monoclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-118032 |
Polyclonal |
WB
IP
IHC
OA
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| antibodies-online | ABIN4330943 |
Polyclonal |
WB
ICC
IHC
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| Atlas Antibodies | HPA018842 |
1 references | Polyclonal |
ICC
IHC
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