BS6645

antibody from Bioworld Technology, Inc
Targeting: KLRD1 CD94
Provider product page for BS6645
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6645 - Provider product page
Provider
Bioworld Technology, Inc
Product name
KLRD1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human KLRD1.
Description
The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired Immuno-globulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoprotein. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ Ï«? T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KLRD1 protein structure - BS6645 shown in red.