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- References [107]
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- Product number
- GTX70174 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70174, RRID:AB_370367
- Product name
- Estrogen Receptor beta antibody [14C8]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Simian
- Host
- Mouse
Submitted references Estrogen receptors participate in carcinogenesis signaling pathways by directly regulating NOD-like receptors.
Steroidogenesis in ovarian-like mesenchymal stroma of hepatic and pancreatic mucinous cystic neoplasms.
Solid papillary carcinoma of the breast with an associated Cytokeratin 7- negative Paget's disease of the nipple. Report of a first case.
Estrogen Receptor β as a Prognostic Marker of Tumor Progression in Colorectal Cancer with Familial Adenomatous Polyposis and Sporadic Polyps.
ERβ Sensitizes NSCLC to Chemotherapy by Regulating DNA Damage Response.
Huntingtin polyQ Mutation Impairs the 17β-Estradiol/Neuroglobin Pathway Devoted to Neuron Survival.
Roles of Aryl Hydrocarbon Receptor in Aromatase-Dependent Cell Proliferation in Human Osteoblasts.
The emerging role of estrogen in B cell malignancies.
Insufficient antibody validation challenges oestrogen receptor beta research.
The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer.
Estrogen receptor β in Merkel cell carcinoma: its possible roles in pathogenesis.
Reproductive steroid receptors and actions in the locus coeruleus of male macaques: Part of an aggression circuit?
Immunohistochemical analysis of steroidogenic enzymes in ovarian-type stroma of pancreatic mucinous cystic neoplasms: Comparative study of subepithelial stromal cells in intraductal papillary mucinous neoplasms of the pancreas.
Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer.
MALAT1 and HOTAIR Long Non-Coding RNAs Play Opposite Role in Estrogen-Mediated Transcriptional Regulation in Prostate Cancer Cells.
Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma.
Biologic roles of estrogen receptor-β and insulin-like growth factor-2 in triple-negative breast cancer.
Prostate tumorigenesis induced by PTEN deletion involves estrogen receptor β repression.
Localization and regulation of reproductive steroid receptors in the raphe serotonin system of male macaques.
ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway.
Loss of ERβ expression in papillary thyroid carcinoma is associated with recurrence in young female.
Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling.
A pilot study comparing the effect of flaxseed, aromatase inhibitor, and the combination on breast tumor biomarkers.
Downregulation of SUN2, a novel tumor suppressor, mediates miR-221/222-induced malignancy in central nervous system embryonal tumors.
ERβ regulates NSCLC phenotypes by controlling oncogenic RAS signaling.
Tissue concentrations of estrogens and aromatase immunolocalization in interstitial pneumonia of human lung.
Expression and subcellular localization of estrogen receptors α and β in human fetal brown adipose tissue.
A phosphotyrosine switch determines the antitumor activity of ERβ.
Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness-a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer.
Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand.
Aromatase in human liver and its diseases.
Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor.
Intratumoral estrogen concentration and expression of estrogen-induced genes in male breast carcinoma: comparison with female breast carcinoma.
Co-expression of estrogen receptor beta and aromatase in Japanese lung cancer patients: gender-dependent clinical outcome.
ERbeta1 represses basal breast cancer epithelial to mesenchymal transition by destabilizing EGFR.
Runt-related transcription factor 2 in human colon carcinoma: a potent prognostic factor associated with estrogen receptor.
Cytoplasmic estrogen receptor β as a potential marker in human non-small cell lung carcinoma.
Differential role of estrogen receptor beta in early versus metastatic non-small cell lung cancer.
Oestrogen receptor β in NSCLC - prevalence, proliferative influence, prognostic impact and smoking.
Estrogen receptor α and β in esophageal squamous cell carcinoma.
Aromatase in colon carcinoma.
Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study.
CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Müllerian tumor).
Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2.
Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathobiological role of androstene-3β, 17β-diol.
Estrogen and progesterone receptor isoform distribution through the menstrual cycle in uteri with and without adenomyosis.
Novel estrogen-related genes and potential biomarkers of ovarian endometriosis identified by differential expression analysis.
Suppression of estrogen actions in human lung cancer.
Co-expression of GPR30 and ERbeta and their association with disease progression in uterine carcinosarcoma.
Vascular leiomyosarcoma: Clinicopathology and immunohistochemistry with special reference to a unique smooth muscle phenotype.
Steroid receptors, HER2/neu and Ki-67, in endometrioid type of endometrial carcinoma: Correlation with conventional histomorphological features of prognosis.
Estrogen receptor beta binds to and regulates three distinct classes of target genes.
Highly concordant coexpression of aromatase and estrogen receptor beta in non-small cell lung cancer.
Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane.
ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading.
Oestrogen receptor beta expression in pleomorphic adenomas of the parotid gland.
Estrogen receptor beta--an independent prognostic marker in estrogen receptor alpha and progesterone receptor-positive breast cancer?
Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation.
Estrogen receptor beta-mediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma.
Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma.
Drug and cell type-specific regulation of genes with different classes of estrogen receptor beta-selective agonists.
Comparative effects of raloxifene, tamoxifen and estradiol on human osteoblasts in vitro: estrogen receptor dependent or independent pathways of raloxifene.
Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors.
Correlated expression of peroxisome proliferator-activated receptor γ with high histologic grade and basal type in invasive ductal carcinoma of the breast
Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcoma.
Estrogen receptors alpha (ESR1) and beta (ESR2) are expressed in circulating human lymphocytes.
Sex steroid receptors expression and hormone-induced cell proliferation in human osteosarcoma.
Inflammatory status influences aromatase and steroid receptor expression in endometriosis.
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer.
Estrogen receptor beta (ERbeta) in endometrial simple hyperplasia and endometrioid carcinoma.
Expression of estrogen receptor beta in normal skin, melanocytic nevi and malignant melanomas.
Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation.
Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer.
17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells.
Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor alpha promoter interaction, and changes in receptor phosphorylation.
Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract.
Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma.
Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.
Estrogen receptor-beta is the predominant estrogen receptor subtype in normal human synovia.
Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients.
Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression.
Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor.
Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.
Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention.
Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex.
Perinatal steroid exposure and respiratory control during early postnatal life.
Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer.
Progesterone receptor in non-small cell lung cancer--a potent prognostic factor and possible target for endocrine therapy.
Estrogen receptors beta4 and beta5 are full length functionally distinct ERbeta isoforms: cloning from human ovary and functional characterization.
Analysis of gene expression induced by diethylstilbestrol (DES) in human primitive Mullerian duct cells using microarray.
Intracellular signaling involved in estrogen regulation of serotonin reuptake.
Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer.
Oestrogen receptor beta: what it means for patients with breast cancer.
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.
Estrogen receptor alpha and beta profiling in human breast cancer.
Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest.
Estrogen and phytoestrogen predispose to erectile dysfunction: do ER-alpha and ER-beta in the cavernosum play a role?
Stable transfection of an estrogen receptor beta cDNA isoform into MDA-MB-231 breast cancer cells.
Expression of estrogen receptors alpha and beta in soft tissue sarcomas: Immunohistochemical and molecular analysis.
Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model.
Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters.
Expression of ERalpha and ERbeta in prostate cancer.
Maximizing production of estrogen receptor beta with the baculovirus expression system.
Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7.
Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor.
Evaluation of seven oestrogen receptor beta antibodies for immunohistochemistry, western blotting, and flow cytometry in human breast tissue.
Fan W, Gao X, Ding C, Lv Y, Shen T, Ma G, Yan L, Song S
Biochemical and biophysical research communications 2019 Apr 2;511(2):468-475
Biochemical and biophysical research communications 2019 Apr 2;511(2):468-475
Steroidogenesis in ovarian-like mesenchymal stroma of hepatic and pancreatic mucinous cystic neoplasms.
Kumata H, Murakami K, Ishida K, Miyagi S, Arakawa A, Inayama Y, Kinowaki K, Ochiai A, Kojima M, Higashi M, Moritani S, Kuwahara K, Nakatani Y, Kajiura D, Tamura G, Kijima H, Yamakawa M, Shiraishi T, Inadome Y, Murakami K, Suzuki H, Sawai T, Unno M, Kamei T, Sasano H
Hepatology research : the official journal of the Japan Society of Hepatology 2018 Nov;48(12):989-999
Hepatology research : the official journal of the Japan Society of Hepatology 2018 Nov;48(12):989-999
Solid papillary carcinoma of the breast with an associated Cytokeratin 7- negative Paget's disease of the nipple. Report of a first case.
Rupp NJ, Rodewald AK, Chiesa F, Varga Z
The breast journal 2018 Jul;24(4):637-641
The breast journal 2018 Jul;24(4):637-641
Estrogen Receptor β as a Prognostic Marker of Tumor Progression in Colorectal Cancer with Familial Adenomatous Polyposis and Sporadic Polyps.
Stevanato Filho PR, Aguiar Júnior S, Begnami MD, Ferreira FO, Nakagawa WT, Spencer RMSB, Bezerra TS, Boggiss PE, Lopes A
Pathology oncology research : POR 2018 Jul;24(3):533-540
Pathology oncology research : POR 2018 Jul;24(3):533-540
ERβ Sensitizes NSCLC to Chemotherapy by Regulating DNA Damage Response.
Nikolos F, Thomas C, Bado I, Gustafsson JÅ
Molecular cancer research : MCR 2018 Feb;16(2):233-242
Molecular cancer research : MCR 2018 Feb;16(2):233-242
Huntingtin polyQ Mutation Impairs the 17β-Estradiol/Neuroglobin Pathway Devoted to Neuron Survival.
Nuzzo MT, Fiocchetti M, Totta P, Melone MAB, Cardinale A, Fusco FR, Gustincich S, Persichetti F, Ascenzi P, Marino M
Molecular neurobiology 2017 Oct;54(8):6634-6646
Molecular neurobiology 2017 Oct;54(8):6634-6646
Roles of Aryl Hydrocarbon Receptor in Aromatase-Dependent Cell Proliferation in Human Osteoblasts.
Miki Y, Hata S, Ono K, Suzuki T, Ito K, Kumamoto H, Sasano H
International journal of molecular sciences 2017 Oct 17;18(10)
International journal of molecular sciences 2017 Oct 17;18(10)
The emerging role of estrogen in B cell malignancies.
Ladikou EE, Kassi E
Leukemia & lymphoma 2017 Mar;58(3):528-539
Leukemia & lymphoma 2017 Mar;58(3):528-539
Insufficient antibody validation challenges oestrogen receptor beta research.
Andersson S, Sundberg M, Pristovsek N, Ibrahim A, Jonsson P, Katona B, Clausson CM, Zieba A, Ramström M, Söderberg O, Williams C, Asplund A
Nature communications 2017 Jun 15;8:15840
Nature communications 2017 Jun 15;8:15840
The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer.
McNamara KM, Oguro S, Omata F, Kikuchi K, Guestini F, Suzuki K, Yang Y, Abe E, Hirakawa H, Brown KA, Takanori I, Ohuchi N, Sasano H
Breast cancer research and treatment 2017 Jan;161(2):213-227
Breast cancer research and treatment 2017 Jan;161(2):213-227
Estrogen receptor β in Merkel cell carcinoma: its possible roles in pathogenesis.
Azmahani A, Nakamura Y, Ishida H, McNamara KM, Fujimura T, Haga T, Hashimoto A, Aiba S, Sasano H
Human pathology 2016 Oct;56:128-33
Human pathology 2016 Oct;56:128-33
Reproductive steroid receptors and actions in the locus coeruleus of male macaques: Part of an aggression circuit?
Bethea CL, Belikova Y, Phu K, Mammerella G
Progress in neuro-psychopharmacology & biological psychiatry 2016 Nov 3;71:210-22
Progress in neuro-psychopharmacology & biological psychiatry 2016 Nov 3;71:210-22
Immunohistochemical analysis of steroidogenic enzymes in ovarian-type stroma of pancreatic mucinous cystic neoplasms: Comparative study of subepithelial stromal cells in intraductal papillary mucinous neoplasms of the pancreas.
Ishida K, Sasano H, Moriya T, Takahashi Y, Sugimoto R, Mue Y, Murakami K, Fujishima F, Nakamura Y, Morikawa T, Motoi F, Suzuki T, Unno M, Sugai T
Pathology international 2016 May;66(5):281-7
Pathology international 2016 May;66(5):281-7
Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer.
Yuan B, Cheng L, Gupta K, Chiang HC, Gupta HB, Sareddy GR, Wang D, Lathrop K, Elledge R, Wang P, McHardy S, Vadlamudi R, Curiel TJ, Hu Y, Ye Q, Li R
Oncotarget 2016 Jul 5;7(27):42585-42597
Oncotarget 2016 Jul 5;7(27):42585-42597
MALAT1 and HOTAIR Long Non-Coding RNAs Play Opposite Role in Estrogen-Mediated Transcriptional Regulation in Prostate Cancer Cells.
Aiello A, Bacci L, Re A, Ripoli C, Pierconti F, Pinto F, Masetti R, Grassi C, Gaetano C, Bassi PF, Pontecorvi A, Nanni S, Farsetti A
Scientific reports 2016 Dec 6;6:38414
Scientific reports 2016 Dec 6;6:38414
Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma.
Sareddy GR, Li X, Liu J, Viswanadhapalli S, Garcia L, Gruslova A, Cavazos D, Garcia M, Strom AM, Gustafsson JA, Tekmal RR, Brenner A, Vadlamudi RK
Scientific reports 2016 Apr 29;6:24185
Scientific reports 2016 Apr 29;6:24185
Biologic roles of estrogen receptor-β and insulin-like growth factor-2 in triple-negative breast cancer.
Hamilton N, Márquez-Garbán D, Mah V, Fernando G, Elshimali Y, Garbán H, Elashoff D, Vadgama J, Goodglick L, Pietras R
BioMed research international 2015;2015:925703
BioMed research international 2015;2015:925703
Prostate tumorigenesis induced by PTEN deletion involves estrogen receptor β repression.
Mak P, Li J, Samanta S, Chang C, Jerry DJ, Davis RJ, Leav I, Mercurio AM
Cell reports 2015 Mar 31;10(12):1982-91
Cell reports 2015 Mar 31;10(12):1982-91
Localization and regulation of reproductive steroid receptors in the raphe serotonin system of male macaques.
Bethea CL, Phu K, Belikova Y, Bethea SC
Journal of chemical neuroanatomy 2015 Jul-Sep;66-67:19-27
Journal of chemical neuroanatomy 2015 Jul-Sep;66-67:19-27
ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway.
Rajapaksa G, Nikolos F, Bado I, Clarke R, Gustafsson JÅ, Thomas C
Oncogene 2015 Jul 30;34(31):4130-41
Oncogene 2015 Jul 30;34(31):4130-41
Loss of ERβ expression in papillary thyroid carcinoma is associated with recurrence in young female.
Ahn HY, Kim MS, Kim MJ, Cho SY, Kim YA, Lee GH, Lee BC, Park YJ, Yi KH
Clinical endocrinology 2015 Feb;82(2):300-6
Clinical endocrinology 2015 Feb;82(2):300-6
Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling.
Maneix L, Antonson P, Humire P, Rochel-Maia S, Castañeda J, Omoto Y, Kim HJ, Warner M, Gustafsson JÅ
Proceedings of the National Academy of Sciences of the United States of America 2015 Apr 21;112(16):5135-40
Proceedings of the National Academy of Sciences of the United States of America 2015 Apr 21;112(16):5135-40
A pilot study comparing the effect of flaxseed, aromatase inhibitor, and the combination on breast tumor biomarkers.
McCann SE, Edge SB, Hicks DG, Thompson LU, Morrison CD, Fetterly G, Andrews C, Clark K, Wilton J, Kulkarni S
Nutrition and cancer 2014;66(4):566-75
Nutrition and cancer 2014;66(4):566-75
Downregulation of SUN2, a novel tumor suppressor, mediates miR-221/222-induced malignancy in central nervous system embryonal tumors.
Hsieh TH, Chien CL, Lee YH, Lin CI, Hsieh JY, Chao ME, Liu DJ, Chu SS, Chen W, Lin SC, Ho DM, Liu RS, Lin CH, Wong TT, Wang HW
Carcinogenesis 2014 Oct;35(10):2164-74
Carcinogenesis 2014 Oct;35(10):2164-74
ERβ regulates NSCLC phenotypes by controlling oncogenic RAS signaling.
Nikolos F, Thomas C, Rajapaksa G, Bado I, Gustafsson JÅ
Molecular cancer research : MCR 2014 Jun;12(6):843-54
Molecular cancer research : MCR 2014 Jun;12(6):843-54
Tissue concentrations of estrogens and aromatase immunolocalization in interstitial pneumonia of human lung.
Taniuchi S, Fujishima F, Miki Y, Abe K, Nakamura Y, Sato S, Kasajima A, Fue M, Ishida K, Watanabe M, Sakakibara T, Maeda S, Suzuki T, Sasano H
Molecular and cellular endocrinology 2014 Jul 5;392(1-2):136-43
Molecular and cellular endocrinology 2014 Jul 5;392(1-2):136-43
Expression and subcellular localization of estrogen receptors α and β in human fetal brown adipose tissue.
Velickovic K, Cvoro A, Srdic B, Stokic E, Markelic M, Golic I, Otasevic V, Stancic A, Jankovic A, Vucetic M, Buzadzic B, Korac B, Korac A
The Journal of clinical endocrinology and metabolism 2014 Jan;99(1):151-9
The Journal of clinical endocrinology and metabolism 2014 Jan;99(1):151-9
A phosphotyrosine switch determines the antitumor activity of ERβ.
Yuan B, Cheng L, Chiang HC, Xu X, Han Y, Su H, Wang L, Zhang B, Lin J, Li X, Xie X, Wang T, Tekmal RR, Curiel TJ, Yuan ZM, Elledge R, Hu Y, Ye Q, Li R
The Journal of clinical investigation 2014 Aug;124(8):3378-90
The Journal of clinical investigation 2014 Aug;124(8):3378-90
Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness-a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer.
Madeira M, Mattar A, Logullo AF, Soares FA, Gebrim LH
BMC cancer 2013 Sep 18;13:425
BMC cancer 2013 Sep 18;13:425
Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand.
Khalaj AJ, Yoon J, Nakai J, Winchester Z, Moore SM, Yoo T, Martinez-Torres L, Kumar S, Itoh N, Tiwari-Woodruff SK
Proceedings of the National Academy of Sciences of the United States of America 2013 Nov 19;110(47):19125-30
Proceedings of the National Academy of Sciences of the United States of America 2013 Nov 19;110(47):19125-30
Aromatase in human liver and its diseases.
Hata S, Miki Y, Saito R, Ishida K, Watanabe M, Sasano H
Cancer medicine 2013 Jun;2(3):305-15
Cancer medicine 2013 Jun;2(3):305-15
Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor.
Verma MK, Miki Y, Abe K, Suzuki T, Niikawa H, Suzuki S, Kondo T, Sasano H
Journal of translational medicine 2013 Jul 9;11:167
Journal of translational medicine 2013 Jul 9;11:167
Intratumoral estrogen concentration and expression of estrogen-induced genes in male breast carcinoma: comparison with female breast carcinoma.
Takagi K, Moriya T, Kurosumi M, Oka K, Miki Y, Ebata A, Toshima T, Tsunekawa S, Takei H, Hirakawa H, Ishida T, Hayashi S, Kurebayashi J, Sasano H, Suzuki T
Hormones & cancer 2013 Feb;4(1):1-11
Hormones & cancer 2013 Feb;4(1):1-11
Co-expression of estrogen receptor beta and aromatase in Japanese lung cancer patients: gender-dependent clinical outcome.
Verma MK, Miki Y, Abe K, Nagasaki S, Niikawa H, Suzuki S, Kondo T, Sasano H
Life sciences 2012 Oct 22;91(15-16):800-8
Life sciences 2012 Oct 22;91(15-16):800-8
ERbeta1 represses basal breast cancer epithelial to mesenchymal transition by destabilizing EGFR.
Thomas C, Rajapaksa G, Nikolos F, Hao R, Katchy A, McCollum CW, Bondesson M, Quinlan P, Thompson A, Krishnamurthy S, Esteva FJ, Gustafsson JÅ
Breast cancer research : BCR 2012 Nov 16;14(6):R148
Breast cancer research : BCR 2012 Nov 16;14(6):R148
Runt-related transcription factor 2 in human colon carcinoma: a potent prognostic factor associated with estrogen receptor.
Sase T, Suzuki T, Miura K, Shiiba K, Sato I, Nakamura Y, Takagi K, Onodera Y, Miki Y, Watanabe M, Ishida K, Ohnuma S, Sasaki H, Sato R, Karasawa H, Shibata C, Unno M, Sasaki I, Sasano H
International journal of cancer 2012 Nov 15;131(10):2284-93
International journal of cancer 2012 Nov 15;131(10):2284-93
Cytoplasmic estrogen receptor β as a potential marker in human non-small cell lung carcinoma.
Verma MK, Miki Y, Abe K, Niikawa H, Sasano H
Expert opinion on therapeutic targets 2012 Mar;16 Suppl 1:S91-102
Expert opinion on therapeutic targets 2012 Mar;16 Suppl 1:S91-102
Differential role of estrogen receptor beta in early versus metastatic non-small cell lung cancer.
Navaratnam S, Skliris G, Qing G, Banerji S, Badiani K, Tu D, Bradbury PA, Leighl NB, Shepherd FA, Nowatzki J, Demers A, Murphy L
Hormones & cancer 2012 Jun;3(3):93-100
Hormones & cancer 2012 Jun;3(3):93-100
Oestrogen receptor β in NSCLC - prevalence, proliferative influence, prognostic impact and smoking.
Karlsson C, Helenius G, Fernandes O, Karlsson MG
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2012 Jun;120(6):451-8
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2012 Jun;120(6):451-8
Estrogen receptor α and β in esophageal squamous cell carcinoma.
Zuguchi M, Miki Y, Onodera Y, Fujishima F, Takeyama D, Okamoto H, Miyata G, Sato A, Satomi S, Sasano H
Cancer science 2012 Jul;103(7):1348-55
Cancer science 2012 Jul;103(7):1348-55
Aromatase in colon carcinoma.
Sato R, Suzuki T, Katayose Y, Miura K, Shiiba K, Miki Y, Kamogawa Y, Yamamoto K, Takayuki 2nd, Egawa S, Unno M, Sasano H
Anticancer research 2012 Aug;32(8):3069-75
Anticancer research 2012 Aug;32(8):3069-75
Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study.
Samartzis N, Samartzis EP, Noske A, Fedier A, Dedes KJ, Caduff R, Fink D, Imesch P
Reproductive biology and endocrinology : RB&E 2012 Apr 20;10:30
Reproductive biology and endocrinology : RB&E 2012 Apr 20;10:30
CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Müllerian tumor).
Choijamts B, Jimi S, Kondo T, Naganuma Y, Matsumoto T, Kuroki M, Iwasaki H, Emoto M
Stem cells (Dayton, Ohio) 2011 Oct;29(10):1485-95
Stem cells (Dayton, Ohio) 2011 Oct;29(10):1485-95
Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2.
Paruthiyil S, Cvoro A, Tagliaferri M, Cohen I, Shtivelman E, Leitman DC
Breast cancer research and treatment 2011 Oct;129(3):777-84
Breast cancer research and treatment 2011 Oct;129(3):777-84
Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathobiological role of androstene-3β, 17β-diol.
Honma N, Saji S, Hirose M, Horiguchi S, Kuroi K, Hayashi S, Utsumi T, Harada N
Cancer science 2011 Oct;102(10):1848-54
Cancer science 2011 Oct;102(10):1848-54
Estrogen and progesterone receptor isoform distribution through the menstrual cycle in uteri with and without adenomyosis.
Mehasseb MK, Panchal R, Taylor AH, Brown L, Bell SC, Habiba M
Fertility and sterility 2011 Jun;95(7):2228-35, 2235.e1
Fertility and sterility 2011 Jun;95(7):2228-35, 2235.e1
Novel estrogen-related genes and potential biomarkers of ovarian endometriosis identified by differential expression analysis.
Vouk K, Smuc T, Guggenberger C, Ribič-Pucelj M, Sinkovec J, Husen B, Thole H, Houba P, Thaete C, Adamski J, Rižner TL
The Journal of steroid biochemistry and molecular biology 2011 Jul;125(3-5):231-42
The Journal of steroid biochemistry and molecular biology 2011 Jul;125(3-5):231-42
Suppression of estrogen actions in human lung cancer.
Miki Y, Abe K, Suzuki S, Suzuki T, Sasano H
Molecular and cellular endocrinology 2011 Jul 4;340(2):168-74
Molecular and cellular endocrinology 2011 Jul 4;340(2):168-74
Co-expression of GPR30 and ERbeta and their association with disease progression in uterine carcinosarcoma.
Huang GS, Gunter MJ, Arend RC, Li M, Arias-Pulido H, Prossnitz ER, Goldberg GL, Smith HO
American journal of obstetrics and gynecology 2010 Sep;203(3):242.e1-5
American journal of obstetrics and gynecology 2010 Sep;203(3):242.e1-5
Vascular leiomyosarcoma: Clinicopathology and immunohistochemistry with special reference to a unique smooth muscle phenotype.
Matsuyama A, Hisaoka M, Hashimoto H
Pathology international 2010 Mar;60(3):212-6
Pathology international 2010 Mar;60(3):212-6
Steroid receptors, HER2/neu and Ki-67, in endometrioid type of endometrial carcinoma: Correlation with conventional histomorphological features of prognosis.
Chakravarty D, Gupta N, Goda JS, Srinivasan R, Patel FD, Dhaliwal L
Acta histochemica 2010 Jul;112(4):355-63
Acta histochemica 2010 Jul;112(4):355-63
Estrogen receptor beta binds to and regulates three distinct classes of target genes.
Vivar OI, Zhao X, Saunier EF, Griffin C, Mayba OS, Tagliaferri M, Cohen I, Speed TP, Leitman DC
The Journal of biological chemistry 2010 Jul 16;285(29):22059-66
The Journal of biological chemistry 2010 Jul 16;285(29):22059-66
Highly concordant coexpression of aromatase and estrogen receptor beta in non-small cell lung cancer.
Abe K, Miki Y, Ono K, Mori M, Kakinuma H, Kou Y, Kudo N, Koguchi M, Niikawa H, Suzuki S, Evans DB, Sugawara S, Suzuki T, Sasano H
Human pathology 2010 Feb;41(2):190-8
Human pathology 2010 Feb;41(2):190-8
Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane.
Vivar OI, Saunier EF, Leitman DC, Firestone GL, Bjeldanes LF
Endocrinology 2010 Apr;151(4):1662-7
Endocrinology 2010 Apr;151(4):1662-7
ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading.
Mak P, Leav I, Pursell B, Bae D, Yang X, Taglienti CA, Gouvin LM, Sharma VM, Mercurio AM
Cancer cell 2010 Apr 13;17(4):319-32
Cancer cell 2010 Apr 13;17(4):319-32
Oestrogen receptor beta expression in pleomorphic adenomas of the parotid gland.
Wong MH, Dobbins TA, Tseung J, Tran N, Lee CS, O'Brien CJ, Clark J, Rose BR
Journal of clinical pathology 2009 Sep;62(9):789-93
Journal of clinical pathology 2009 Sep;62(9):789-93
Estrogen receptor beta--an independent prognostic marker in estrogen receptor alpha and progesterone receptor-positive breast cancer?
Maehle BO, Collett K, Tretli S, Akslen LA, Grotmol T
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Sep;117(9):644-50
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Sep;117(9):644-50
Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation.
Raso MG, Behrens C, Herynk MH, Liu S, Prudkin L, Ozburn NC, Woods DM, Tang X, Mehran RJ, Moran C, Lee JJ, Wistuba II
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Sep 1;15(17):5359-68
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Sep 1;15(17):5359-68
Estrogen receptor beta-mediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma.
Urbanska K, Pannizzo P, Lassak A, Gualco E, Surmacz E, Croul S, Del Valle L, Khalili K, Reiss K
Journal of cellular physiology 2009 May;219(2):392-401
Journal of cellular physiology 2009 May;219(2):392-401
Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma.
Belcher SM, Ma X, Le HH
Endocrinology 2009 Mar;150(3):1112-21
Endocrinology 2009 Mar;150(3):1112-21
Drug and cell type-specific regulation of genes with different classes of estrogen receptor beta-selective agonists.
Paruthiyil S, Cvoro A, Zhao X, Wu Z, Sui Y, Staub RE, Baggett S, Herber CB, Griffin C, Tagliaferri M, Harris HA, Cohen I, Bjeldanes LF, Speed TP, Schaufele F, Leitman DC
PloS one 2009 Jul 17;4(7):e6271
PloS one 2009 Jul 17;4(7):e6271
Comparative effects of raloxifene, tamoxifen and estradiol on human osteoblasts in vitro: estrogen receptor dependent or independent pathways of raloxifene.
Miki Y, Suzuki T, Nagasaki S, Hata S, Akahira J, Sasano H
The Journal of steroid biochemistry and molecular biology 2009 Feb;113(3-5):281-9
The Journal of steroid biochemistry and molecular biology 2009 Feb;113(3-5):281-9
Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors.
Sato R, Suzuki T, Katayose Y, Miura K, Shiiba K, Tateno H, Miki Y, Akahira J, Kamogawa Y, Nagasaki S, Yamamoto K, Ii T, Egawa S, Evans DB, Unno M, Sasano H
Cancer research 2009 Feb 1;69(3):914-22
Cancer research 2009 Feb 1;69(3):914-22
Correlated expression of peroxisome proliferator-activated receptor γ with high histologic grade and basal type in invasive ductal carcinoma of the breast
Jeong H, Lee Y, An J, Woo O, Park K, Kim A
Basic and Applied Pathology 2009 December;2(4):118-124
Basic and Applied Pathology 2009 December;2(4):118-124
Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcoma.
Huang GS, Arend RC, Li M, Gunter MJ, Chiu LG, Horwitz SB, Goldberg GL
American journal of obstetrics and gynecology 2009 Apr;200(4):457.e1-5
American journal of obstetrics and gynecology 2009 Apr;200(4):457.e1-5
Estrogen receptors alpha (ESR1) and beta (ESR2) are expressed in circulating human lymphocytes.
Scariano JK, Emery-Cohen AJ, Pickett GG, Morgan M, Simons PC, Alba F
Journal of receptor and signal transduction research 2008;28(3):285-93
Journal of receptor and signal transduction research 2008;28(3):285-93
Sex steroid receptors expression and hormone-induced cell proliferation in human osteosarcoma.
Dohi O, Hatori M, Suzuki T, Ono K, Hosaka M, Akahira J, Miki Y, Nagasaki S, Itoi E, Sasano H
Cancer science 2008 Mar;99(3):518-23
Cancer science 2008 Mar;99(3):518-23
Inflammatory status influences aromatase and steroid receptor expression in endometriosis.
Bukulmez O, Hardy DB, Carr BR, Word RA, Mendelson CR
Endocrinology 2008 Mar;149(3):1190-204
Endocrinology 2008 Mar;149(3):1190-204
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
Setlur SR, Mertz KD, Hoshida Y, Demichelis F, Lupien M, Perner S, Sboner A, Pawitan Y, Andrén O, Johnson LA, Tang J, Adami HO, Calza S, Chinnaiyan AM, Rhodes D, Tomlins S, Fall K, Mucci LA, Kantoff PW, Stampfer MJ, Andersson SO, Varenhorst E, Johansson JE, Brown M, Golub TR, Rubin MA
Journal of the National Cancer Institute 2008 Jun 4;100(11):815-25
Journal of the National Cancer Institute 2008 Jun 4;100(11):815-25
Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer.
Jones LP, Tilli MT, Assefnia S, Torre K, Halama ED, Parrish A, Rosen EM, Furth PA
Oncogene 2008 Jan 31;27(6):794-802
Oncogene 2008 Jan 31;27(6):794-802
Estrogen receptor beta (ERbeta) in endometrial simple hyperplasia and endometrioid carcinoma.
Chakravarty D, Srinivasan R, Ghosh S, Rajwanshi A, Gopalan S
Applied immunohistochemistry & molecular morphology : AIMM 2008 Dec;16(6):535-42
Applied immunohistochemistry & molecular morphology : AIMM 2008 Dec;16(6):535-42
Expression of estrogen receptor beta in normal skin, melanocytic nevi and malignant melanomas.
Ohata C, Tadokoro T, Itami S
The Journal of dermatology 2008 Apr;35(4):215-21
The Journal of dermatology 2008 Apr;35(4):215-21
Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation.
Galluzzo P, Caiazza F, Moreno S, Marino M
Endocrine-related cancer 2007 Mar;14(1):153-67
Endocrine-related cancer 2007 Mar;14(1):153-67
Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer.
Skliris GP, Lewis A, Emberley E, Peng B, Weebadda WK, Kemp A, Davie JR, Shiu RP, Watson PH, Murphy LC
Breast cancer research and treatment 2007 Jul;104(1):75-85
Breast cancer research and treatment 2007 Jul;104(1):75-85
17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells.
Caiazza F, Galluzzo P, Lorenzetti S, Marino M
Biochemical and biophysical research communications 2007 Jul 20;359(1):102-7
Biochemical and biophysical research communications 2007 Jul 20;359(1):102-7
Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor alpha promoter interaction, and changes in receptor phosphorylation.
Al-Dhaheri MH, Rowan BG
Molecular endocrinology (Baltimore, Md.) 2007 Feb;21(2):439-56
Molecular endocrinology (Baltimore, Md.) 2007 Feb;21(2):439-56
Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract.
Cvoro A, Paruthiyil S, Jones JO, Tzagarakis-Foster C, Clegg NJ, Tatomer D, Medina RT, Tagliaferri M, Schaufele F, Scanlan TS, Diamond MI, Cohen I, Leitman DC
Endocrinology 2007 Feb;148(2):538-47
Endocrinology 2007 Feb;148(2):538-47
Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma.
Gruvberger-Saal SK, Bendahl PO, Saal LH, Laakso M, Hegardt C, Edén P, Peterson C, Malmström P, Isola J, Borg A, Fernö M
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Apr 1;13(7):1987-94
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Apr 1;13(7):1987-94
Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.
Skliris GP, Leygue E, Curtis-Snell L, Watson PH, Murphy LC
British journal of cancer 2006 Sep 4;95(5):616-26
British journal of cancer 2006 Sep 4;95(5):616-26
Estrogen receptor-beta is the predominant estrogen receptor subtype in normal human synovia.
Dietrich W, Haitel A, Holzer G, Huber JC, Kolbus A, Tschugguel W
Journal of the Society for Gynecologic Investigation 2006 Oct;13(7):512-7
Journal of the Society for Gynecologic Investigation 2006 Oct;13(7):512-7
Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients.
Savinov AY, Remacle AG, Golubkov VS, Krajewska M, Kennedy S, Duffy MJ, Rozanov DV, Krajewski S, Strongin AY
Cancer research 2006 Mar 1;66(5):2716-24
Cancer research 2006 Mar 1;66(5):2716-24
Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression.
Cvoro A, Tzagarakis-Foster C, Tatomer D, Paruthiyil S, Fox MS, Leitman DC
Molecular cell 2006 Feb 17;21(4):555-64
Molecular cell 2006 Feb 17;21(4):555-64
Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor.
Zheng FF, Wu RC, Smith CL, O'Malley BW
Molecular and cellular biology 2005 Sep;25(18):8273-84
Molecular and cellular biology 2005 Sep;25(18):8273-84
Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.
Helguero LA, Faulds MH, Gustafsson JA, Haldosén LA
Oncogene 2005 Oct 6;24(44):6605-16
Oncogene 2005 Oct 6;24(44):6605-16
Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention.
Poola I, Fuqua SA, De Witty RL, Abraham J, Marshallack JJ, Liu A
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Oct 15;11(20):7579-85
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Oct 15;11(20):7579-85
Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex.
Schwartz AG, Prysak GM, Murphy V, Lonardo F, Pass H, Schwartz J, Brooks S
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Oct 15;11(20):7280-7
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Oct 15;11(20):7280-7
Perinatal steroid exposure and respiratory control during early postnatal life.
Soliz J, Joseph V
Respiratory physiology & neurobiology 2005 Nov 15;149(1-3):111-22
Respiratory physiology & neurobiology 2005 Nov 15;149(1-3):111-22
Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer.
Jones LP, Li M, Halama ED, Ma Y, Lubet R, Grubbs CJ, Deng CX, Rosen EM, Furth PA
Oncogene 2005 May 19;24(22):3554-62
Oncogene 2005 May 19;24(22):3554-62
Progesterone receptor in non-small cell lung cancer--a potent prognostic factor and possible target for endocrine therapy.
Ishibashi H, Suzuki T, Suzuki S, Niikawa H, Lu L, Miki Y, Moriya T, Hayashi S, Handa M, Kondo T, Sasano H
Cancer research 2005 Jul 15;65(14):6450-8
Cancer research 2005 Jul 15;65(14):6450-8
Estrogen receptors beta4 and beta5 are full length functionally distinct ERbeta isoforms: cloning from human ovary and functional characterization.
Poola I, Abraham J, Baldwin K, Saunders A, Bhatnagar R
Endocrine 2005 Aug;27(3):227-38
Endocrine 2005 Aug;27(3):227-38
Analysis of gene expression induced by diethylstilbestrol (DES) in human primitive Mullerian duct cells using microarray.
Miki Y, Suzuki T, Tazawa C, Ishizuka M, Semba S, Gorai I, Sasano H
Cancer letters 2005 Apr 8;220(2):197-210
Cancer letters 2005 Apr 8;220(2):197-210
Intracellular signaling involved in estrogen regulation of serotonin reuptake.
Koldzic-Zivanovic N, Seitz PK, Watson CS, Cunningham KA, Thomas ML
Molecular and cellular endocrinology 2004 Oct 29;226(1-2):33-42
Molecular and cellular endocrinology 2004 Oct 29;226(1-2):33-42
Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer.
Hopp TA, Weiss HL, Parra IS, Cui Y, Osborne CK, Fuqua SA
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Nov 15;10(22):7490-9
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Nov 15;10(22):7490-9
Oestrogen receptor beta: what it means for patients with breast cancer.
Speirs V, Carder PJ, Lane S, Dodwell D, Lansdown MR, Hanby AM
The Lancet. Oncology 2004 Mar;5(3):174-81
The Lancet. Oncology 2004 Mar;5(3):174-81
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.
Tee MK, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ, Yamamoto KR, Leitman DC
Molecular biology of the cell 2004 Mar;15(3):1262-72
Molecular biology of the cell 2004 Mar;15(3):1262-72
Estrogen receptor alpha and beta profiling in human breast cancer.
Balfe P, McCann A, McGoldrick A, McAllister K, Kennedy M, Dervan P, Kerin MJ
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2004 Jun;30(5):469-74
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2004 Jun;30(5):469-74
Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest.
Paruthiyil S, Parmar H, Kerekatte V, Cunha GR, Firestone GL, Leitman DC
Cancer research 2004 Jan 1;64(1):423-8
Cancer research 2004 Jan 1;64(1):423-8
Estrogen and phytoestrogen predispose to erectile dysfunction: do ER-alpha and ER-beta in the cavernosum play a role?
Srilatha B, Adaikan PG
Urology 2004 Feb;63(2):382-6
Urology 2004 Feb;63(2):382-6
Stable transfection of an estrogen receptor beta cDNA isoform into MDA-MB-231 breast cancer cells.
Tonetti DA, Rubenstein R, DeLeon M, Zhao H, Pappas SG, Bentrem DJ, Chen B, Constantinou A, Craig Jordan V
The Journal of steroid biochemistry and molecular biology 2003 Oct;87(1):47-55
The Journal of steroid biochemistry and molecular biology 2003 Oct;87(1):47-55
Expression of estrogen receptors alpha and beta in soft tissue sarcomas: Immunohistochemical and molecular analysis.
Li XQ, Hisaoka M, Hashimoto H
Pathology international 2003 Oct;53(10):671-9
Pathology international 2003 Oct;53(10):671-9
Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model.
Skliris GP, Munot K, Bell SM, Carder PJ, Lane S, Horgan K, Lansdown MR, Parkes AT, Hanby AM, Markham AF, Speirs V
The Journal of pathology 2003 Oct;201(2):213-20
The Journal of pathology 2003 Oct;201(2):213-20
Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters.
Fuqua SA, Schiff R, Parra I, Moore JT, Mohsin SK, Osborne CK, Clark GM, Allred DC
Cancer research 2003 May 15;63(10):2434-9
Cancer research 2003 May 15;63(10):2434-9
Expression of ERalpha and ERbeta in prostate cancer.
Linja MJ, Savinainen KJ, Tammela TL, Isola JJ, Visakorpi T
The Prostate 2003 May 15;55(3):180-6
The Prostate 2003 May 15;55(3):180-6
Maximizing production of estrogen receptor beta with the baculovirus expression system.
Kulakosky PC, Klinge CM
BioTechniques 2003 Feb;34(2):334-8, 340-3
BioTechniques 2003 Feb;34(2):334-8, 340-3
Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7.
Omoto Y, Eguchi H, Yamamoto-Yamaguchi Y, Hayashi S
Oncogene 2003 Aug 7;22(32):5011-20
Oncogene 2003 Aug 7;22(32):5011-20
Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor.
Saji S, Omoto Y, Shimizu C, Warner M, Hayashi Y, Horiguchi S, Watanabe T, Hayashi S, Gustafsson JA, Toi M
Cancer research 2002 Sep 1;62(17):4849-53
Cancer research 2002 Sep 1;62(17):4849-53
Evaluation of seven oestrogen receptor beta antibodies for immunohistochemistry, western blotting, and flow cytometry in human breast tissue.
Skliris GP, Parkes AT, Limer JL, Burdall SE, Carder PJ, Speirs V
The Journal of pathology 2002 Jun;197(2):155-62
The Journal of pathology 2002 Jun;197(2):155-62
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Enhanced validation
Supportive validation
- Submitted by
- Ahmedibrahim78
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- This antibody detects recombinant ERbeta and ERbeta expressing HCT116 cells. However, it detects also a similar band of negative cells.
- Sample type
- HCT116 cell line
- Primary Ab dilution
- 1:1000
- Secondary Ab dilution
- Protocol
- https://www.nature.com/articles/ncomms15840
- Control image
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Non-transfected (¡V) and transfected (+) 293T whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody (GTX70174) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Non-transfected (¡V) and transfected (+) 293T whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody [14C8] (GTX70174) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- B. Infiltrating lobular carcinoma of the breast.
