Tissue expression
Cell line expression
Protein structure
MACC1
MET transcriptional regulator MACC17A5, SH3BP4L
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]). [supplied by OMIM, Mar 2009]
Top validated antibodies |
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antibodies-online | ![]() |
4 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Abnova Corporation | ![]() |
7 references | Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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