BS1627

antibody from Bioworld Technology, Inc
Targeting: CSF1R C-FMS, CD115, CSFR, FMS
Provider product page for BS1627
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS1627 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1627, RRID:AB_1662075
Product name
c Fms (E557) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 531-580 of Human c-Fms.
Description
c-Fms/CSF-1R is a transmembrane tyrosine kinase receptor belonging to the CSF1/PDGF receptor family. It is encoded by the c-Fms proto-oncogene and is expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells and some myoblasts. It is important for growth and differentiation of myeloid cells and its function can be regulated by SLAP-2. c-Fms/CSF-1R is responsible for mediating all of the functions of M-CSF. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CSF1R protein structure - BS1627 shown in red.