CABT-BL7399

antibody from Creative Diagnostics

Targeting: CSF1R C-FMS, CD115, CSFR, FMS

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

CABT-BL7399

Provider

Creative Diagnostics

Product name

Anti-CSF1R Monoclonal antibody, clone BGT09

Antibody type

Monoclonal

Description

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Isotype

IgG