BS6464

antibody from Bioworld Technology, Inc
Targeting: MAPK3 ERK1, p44erk1, p44mapk, PRKM3
Provider product page for BS6464
Western blot
Immunohistochemistry

Antibody data

Product number
BS6464 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ERK1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ERK1.
Description
The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and Threonine sites mapping within a characteristic Thr- Glu-Tyr motif. Phosphorylation at both the Thr and Tyr residues is required for full enzymatic activation. In response to activation, MAP kinases phos-phorylate downstream components on Serine and Threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. The ERK family has three additional members: ERK 3, ERK 5 and ERK 6.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MAPK3 protein structure - BS6464 shown in red.