APC00014G

antibody from Leading Biology

Targeting: ANKLE2 KIAA0692, Lem4, LEMD7

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APC00014G

Provider

Leading Biology

Product name

KIAA0692 / ANKLE2 Antibody (Internal)

Antibody type

Polyclonal

Description

Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.

Reactivity

Human, Mouse, Rat

Host

Chicken/Avian

Isotype

IgY

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.