Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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Validation data
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- Product number
- MB0061 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CHD3 (C terminus) monoclonal antibody
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide, corresponding to the C-terminus of Human CHD3.
- Description
- This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot detection of CHD3 antibody in Y79&Raji cell lysates using CHD3 antibody (1:1000 diluted) .