MB0061

antibody from Bioworld Technology, Inc
Targeting: CHD3 Mi-2a, Mi2-ALPHA, ZFH
Provider product page for MB0061
Western blot
Immunohistochemistry
Flow cytometry

Antibody data

Product number
MB0061 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CHD3 (C terminus) monoclonal antibody
Antibody type
Monoclonal
Antigen
Synthetic peptide, corresponding to the C-terminus of Human CHD3.
Description
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Reactivity
Human
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CHD3 protein structure - MB0061 shown in red.