Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16086-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16086-1-AP, RRID:AB_2181432
- Product name
- RPL23 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPL23 antibody (Cat. #16086-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Triptolide interrupts rRNA synthesis and induces the RPL23‑MDM2‑p53 pathway to repress lung cancer cells.
Proteomics profiling and pathway analysis of hippocampal aging in rhesus monkeys.
Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling.
Altered expression of insulin-degrading enzyme and regulator of calcineurin in the rat intracerebral streptozotocin model and human apolipoprotein E-ε4-associated Alzheimer's disease.
Therapeutic Advantages of Dual Targeting of PPAR-δ and PPAR-γ in an Experimental Model of Sporadic Alzheimer's Disease.
Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease.
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome.
LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.
Defective ribosome assembly in Shwachman-Diamond syndrome.
Wang J, Zhang ZQ, Li FQ, Chen JN, Gong X, Cao BB, Wang W
Oncology reports 2020 Jun;43(6):1863-1874
Oncology reports 2020 Jun;43(6):1863-1874
Proteomics profiling and pathway analysis of hippocampal aging in rhesus monkeys.
Meng S, Xia W, Pan M, Jia Y, He Z, Ge W
BMC neuroscience 2020 Jan 15;21(1):2
BMC neuroscience 2020 Jan 15;21(1):2
Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling.
Evans HT, Benetatos J, van Roijen M, Bodea LG, Götz J
The EMBO journal 2019 Jul 1;38(13):e101174
The EMBO journal 2019 Jul 1;38(13):e101174
Altered expression of insulin-degrading enzyme and regulator of calcineurin in the rat intracerebral streptozotocin model and human apolipoprotein E-ε4-associated Alzheimer's disease.
Delikkaya B, Moriel N, Tong M, Gallucci G, de la Monte SM
Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Dec;11:392-404
Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Dec;11:392-404
Therapeutic Advantages of Dual Targeting of PPAR-δ and PPAR-γ in an Experimental Model of Sporadic Alzheimer's Disease.
Reich D, Gallucci G, Tong M, de la Monte SM
Journal of Parkinson's disease and Alzheimer's disease 2018 May;5(1)
Journal of Parkinson's disease and Alzheimer's disease 2018 May;5(1)
Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease.
de la Monte SM, Tong M, Schiano I, Didsbury J
Journal of Alzheimer's disease : JAD 2017;55(2):849-864
Journal of Alzheimer's disease : JAD 2017;55(2):849-864
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome.
Qi Y, Li X, Chang C, Xu F, He Q, Zhao Y, Wu L
Scientific reports 2017 May 24;7(1):2323
Scientific reports 2017 May 24;7(1):2323
LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.
Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ
Nature cell biology 2017 Jan;19(1):60-67
Nature cell biology 2017 Jan;19(1):60-67
Defective ribosome assembly in Shwachman-Diamond syndrome.
Wong CC, Traynor D, Basse N, Kay RR, Warren AJ
Blood 2011 Oct 20;118(16):4305-12
Blood 2011 Oct 20;118(16):4305-12
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 16086-1-AP(RPL23 antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16086-1-AP(RPL23 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RPL23 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPL23. This antibody recognizes human, mouse, rat antigen. The RPL23 antibody has been validated for the following applications: ELISA, WB, IHC analysis.