Tissue expression
Cell line expression
Protein structure
GGCT
Gamma-glutamylcyclotransferaseC7orf24, CRF21, GCTG, Ggc, MGC3077
The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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Proteintech Group | ![]() |
7 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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