Explore
Validate
Learn
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- FAB145P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CCR1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CCR1. Reacts specifically with human CCR1 transfectants and not the parental cell line in flow cytometry. No cross-reactivity with CCR5 transfectants is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P32246- Isotype
- IgG
- Antibody clone number
- 53504
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis.
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity.
IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis.
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities.
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation.
Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality.
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces.
Armas-González E, Domínguez-Luis MJ, Díaz-Martín A, Arce-Franco M, Castro-Hernández J, Danelon G, Hernández-Hernández V, Bustabad-Reyes S, Cantabrana A, Uguccioni M, Díaz-González F
Arthritis research & therapy 2018 Jun 7;20(1):114
Arthritis research & therapy 2018 Jun 7;20(1):114
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Faulkner L, Gibson A, Sullivan A, Tailor A, Usui T, Alfirevic A, Pirmohamed M, Naisbitt DJ, Kevin Park B
Toxicological sciences : an official journal of the Society of Toxicology 2016 Dec;154(2):416-429
Toxicological sciences : an official journal of the Society of Toxicology 2016 Dec;154(2):416-429
TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity.
Geng D, Kaczanowska S, Tsai A, Younger K, Ochoa A, Rapoport AP, Ostrand-Rosenberg S, Davila E
Cancer research 2015 May 15;75(10):1959-1971
Cancer research 2015 May 15;75(10):1959-1971
IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis.
Broux B, Mizee MR, Vanheusden M, van der Pol S, van Horssen J, Van Wijmeersch B, Somers V, de Vries HE, Stinissen P, Hellings N
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 1;194(5):2099-109
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 1;194(5):2099-109
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.
Vujanovic L, Ballard W, Thorne SH, Vujanovic NL, Butterfield LH
Oncoimmunology 2012 Jul 1;1(4):448-457
Oncoimmunology 2012 Jul 1;1(4):448-457
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Badr G, Lefevre EA, Mohany M
PloS one 2011;6(9):e23741
PloS one 2011;6(9):e23741
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, Traidl-Hoffman C, Behrendt H, Cavani A
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities.
Barroso-González J, El Jaber-Vazdekis N, García-Expósito L, Machado JD, Zárate R, Ravelo AG, Estévez-Braun A, Valenzuela-Fernández A
The Journal of biological chemistry 2009 Jun 12;284(24):16609-20
The Journal of biological chemistry 2009 Jun 12;284(24):16609-20
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Ahern D, Lloyd CM, Robinson DS
Allergy 2009 Aug;64(8):1121-9
Allergy 2009 Aug;64(8):1121-9
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
Pokkali S, Das SD, R L
Cytokine 2008 Mar;41(3):307-14
Cytokine 2008 Mar;41(3):307-14
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8053-67
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8053-67
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.
Bestebroer J, Poppelier MJ, Ulfman LH, Lenting PJ, Denis CV, van Kessel KP, van Strijp JA, de Haas CJ
Blood 2007 Apr 1;109(7):2936-43
Blood 2007 Apr 1;109(7):2936-43
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
International journal of cancer 2006 May 1;118(9):2147-57
International journal of cancer 2006 May 1;118(9):2147-57
Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation.
Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, Trentin L, Zamarchi R, Tamamura H, Fujii N, Semenzato G, Chieco-Bianchi L, Amadori A
Blood 2005 Feb 1;105(3):931-9
Blood 2005 Feb 1;105(3):931-9
Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality.
Chang WL, Baumgarth N, Yu D, Barry PA
Journal of virology 2004 Aug;78(16):8720-31
Journal of virology 2004 Aug;78(16):8720-31
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Liu LY, Jarjour NN, Busse WW, Kelly EA
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
Journal of leukocyte biology 2003 May;73(5):584-90
Journal of leukocyte biology 2003 May;73(5):584-90
Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces.
Vanbervliet B, Homey B, Durand I, Massacrier C, Aït-Yahia S, de Bouteiller O, Vicari A, Caux C
European journal of immunology 2002 Jan;32(1):231-42
European journal of immunology 2002 Jan;32(1):231-42
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human CCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB145P) or (B) Mouse IgG2B Phycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.
