Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [2]
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Validation data
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- Product number
- MAB646 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IL-18/IL-1F4 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects the pro region of human IL-18/IL-1F4 in direct ELISAs and Western blots. Does not cross-react with recombinant human IL-18, recombinant mouse IL-18 or recombinant rat IL-18.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references NLRP3 inflammasome: a novel link between lipoproteins and atherosclerosis.
IL-18 Is Involved in Eosinophil-Mediated Tumoricidal Activity against a Colon Carcinoma Cell Line by Upregulating LFA-1 and ICAM-1.
IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
Li WL, Hua LG, Qu P, Yan WH, Ming C, Jun YD, Yuan LD, Nan N
Archives of medical science : AMS 2016 Oct 1;12(5):950-958
Archives of medical science : AMS 2016 Oct 1;12(5):950-958
IL-18 Is Involved in Eosinophil-Mediated Tumoricidal Activity against a Colon Carcinoma Cell Line by Upregulating LFA-1 and ICAM-1.
Gatault S, Delbeke M, Driss V, Sarazin A, Dendooven A, Kahn JE, Lefèvre G, Capron M
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 1;195(5):2483-92
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 1;195(5):2483-92
IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1642-52
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1642-52
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human IL-18/IL-1F4 by Western Blot. Detection of Human IL-18/IL-1F4 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of IL-18/IL-1F4 in Human PBMCs by Flow Cytometry. Detection of IL-18/IL-1F4 in Human PBMCs by Flow Cytometry.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of IL-18/IL-1F4 Propeptide in Human THP-1 cells by Flow Cytometry. Detection of IL-18/IL-1F4 Propeptide in Human THP-1 cells by Flow Cytometry.