D043-3

antibody from R&D Systems

Targeting: IL18 IGIF, IL-18, IL-1g, IL1F4

Western blot (Data presented on provider website)

Antibody Data

Product number

D043-3

Provider

R&D Systems

Product name

Human IL-18/IL-1F4 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. This antibody reacts with human IL-18 on Western blotting.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

25-2G

Vial size

100 ug

Storage

This antibody is stable for one year from the date of purchase when stored at 4°C. After reconstitution, avoid repeated freezing and thawing. For storage, prepare appropriate aliquots and freeze at -20°C.

References

Submitted references

Zinc inhibits high glucose-induced NLRP3 inflammasome activation in human peritoneal mesothelial cells.

Fan Y, Zhang X, Yang L, Wang J, Hu Y, Bian A, Liu J, Ma J
Molecular medicine reports 2017 Oct;16(4):5195-5202

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Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.

Venkatesan B, Valente AJ, Reddy VS, Siwik DA, Chandrasekar B
American journal of physiology. Heart and circulatory physiology 2009 Aug;297(2):H874-86

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Clinical improvement in chronic plaque-type psoriasis lesions after narrow-band UVB therapy is accompanied by a decrease in the expression of IFN-gamma inducers -- IL-12, IL-18 and IL-23.

Piskin G, Tursen U, Sylva-Steenland RM, Bos JD, Teunissen MB
Experimental dermatology 2004 Dec;13(12):764-72

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Cytokine profile of the rheumatoid nodule suggests that it is a Th1 granuloma.

Hessian PA, Highton J, Kean A, Sun CK, Chin M
Arthritis and rheumatism 2003 Feb;48(2):334-8