D045-6

antibody from R&D Systems

Targeting: IL18 IGIF, IL-18, IL-1g, IL1F4

ELISA (Data presented on provider website)

Antibody Data

Product number

D045-6

Provider

R&D Systems

Product name

Human IL-18/IL-1F4 Biotinylated Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. This antibody reacts with human IL-18 on ELISA.

Reactivity

Human

Host

Rat

Conjugate

Biotin

Isotype

IgG

Antibody clone number

159-12B

Vial size

50 uL

Storage

This antibody solution is stable for one year from the date of purchase when stored at 4°C.

References

Submitted references

Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j.

Nuñez SY, Ziblat A, Secchiari F, Torres NI, Sierra JM, Raffo Iraolagoitia XL, Araya RE, Domaica CI, Fuertes MB, Zwirner NW
Journal of immunology (Baltimore, Md. : 1950) 2018 Feb 1;200(3):1008-1015

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Production and regulation of interleukin-1 family cytokines at the materno-fetal interface.

Scott LM, Bryant AH, Rees A, Down B, Jones RH, Thornton CA
Cytokine 2017 Nov;99:194-202

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IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.

Briend E, Ferguson GJ, Mori M, Damera G, Stephenson K, Karp NA, Sethi S, Ward CK, Sleeman MA, Erjefält JS, Finch DK
Respiratory research 2017 Aug 22;18(1):159

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Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors.

Spallanzani RG, Torres NI, Avila DE, Ziblat A, Iraolagoitia XL, Rossi LE, Domaica CI, Fuertes MB, Rabinovich GA, Zwirner NW
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 1;195(5):2141-8

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Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1.

Jitprasertwong P, Jaedicke KM, Nile CJ, Preshaw PM, Taylor JJ
Cytokine 2014 Feb;65(2):222-30

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Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.

Hu H, Kwun J, Aizenstein BD, Knechtle SJ
Transplantation 2009 Jun 27;87(12):1814-20

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Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects.

Madsen EL, Bruun JM, Skogstrand K, Hougaard DM, Christiansen T, Richelsen B
Metabolism: clinical and experimental 2009 Jul;58(7):946-53

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Development and validation of sandwich ELISA microarrays with minimal assay interference.

Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC
Journal of proteome research 2008 Jun;7(6):2406-14

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Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.

Pfleger C, Schloot N, ter Veld F
Journal of immunological methods 2008 Jan 1;329(1-2):214-8