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- Antigen structure
- References [4]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500686 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- SCO1 antibody was raised against a 14 amino acid peptide from near the center of human SCO1.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Human Sco1 functional studies and pathological implications of the P174L mutant.
Human Sco1 and Sco2 function as copper-binding proteins.
Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy.
SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae.
Banci L, Bertini I, Ciofi-Baffoni S, Leontari I, Martinelli M, Palumaa P, Sillard R, Wang S
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 2;104(1):15-20
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 2;104(1):15-20
Human Sco1 and Sco2 function as copper-binding proteins.
Horng YC, Leary SC, Cobine PA, Young FB, George GN, Shoubridge EA, Winge DR
The Journal of biological chemistry 2005 Oct 7;280(40):34113-22
The Journal of biological chemistry 2005 Oct 7;280(40):34113-22
Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy.
Valnot I, Osmond S, Gigarel N, Mehaye B, Amiel J, Cormier-Daire V, Munnich A, Bonnefont JP, Rustin P, Rötig A
American journal of human genetics 2000 Nov;67(5):1104-9
American journal of human genetics 2000 Nov;67(5):1104-9
SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae.
Glerum DM, Shtanko A, Tzagoloff A
The Journal of biological chemistry 1996 Aug 23;271(34):20531-5
The Journal of biological chemistry 1996 Aug 23;271(34):20531-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SCO1 in human brain tissue lysate with AP30766PU-N at (A) 0.5 and (B) 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of SCO1 in human brain tissue with AP30766PU-N at 2.5 ?g/ml.
