SIG-3614

antibody from BioLegend (formerly Covance Antibody Products)
Targeting: MUC1 ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM
Provider product page for SIG-3614
Immunohistochemistry

Antibody data

Product number
SIG-3614 - Provider product page
Provider
BioLegend (formerly Covance Antibody Products)
Product name
anti-CA 15-3
Antibody type
Monoclonal
Antigen
This antibody was generated against a membrane-enriched fraction of a human carcinoma metastatic to the liver.
Description
Purified Antibody
Reactivity
Human
Host
Mouse
Epitope
DF3 recognizes a 290 kDa antigenic determinant on a mucin-like glycoprotein present on apical borders of secretory mammary epithelial cells and the cytosol of less differentiated cells. Malignant tumors display cytoplasmic expression while in benign tumors, expression is seen on apical surfaces.
Isotype
IgG
Antibody clone number
DF3
Vial size
200 µl
MUC1 protein structure - SIG-3614 shown in red.