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LearnV3962
antibody from NSJ Bioreagents
Targeting: MUC1
ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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- Product number
- V3962 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- MUC1 Antibody / Mucin-1
- Antibody type
- Monoclonal
- Description
- Protein G affinity chromatography
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 115D8
- Vial size
- 20 µg, 100 µg (with BSA, sodium azide), 100 µg (without BSA, sodium azide), 7 ml (prediluted for IHC)
- Concentration
- 0.2 mg/ml, 1 mg/ml (BSA/azide free format), Prediluted (IHC only format)
- Storage
- Store the MUC1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Submitted references TA-MUC1 as detected by the fully humanized, therapeutic antibody Gatipotzumab predicts poor prognosis in cervical cancer.
Cross-reactivity between MUC1 antigen and MCA: false elevation of serum CA 15-3 level in pregnant and lactating women by Ma695-Ma552-based assay.
Use of CA15‑3 for screening breast cancer: An antibody‑lectin sandwich assay for detecting glycosylation of CA15‑3 in sera.
Inverse association of rab31 and mucin-1 (CA15-3) antigen levels in estrogen receptor-positive (ER+) breast cancer tissues with clinicopathological parameters and patients' prognosis.
Binding of circulating anti-MUC1 antibody and serum MUC1 antigen in stage IV breast cancer.
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.
p53 determines prognostic significance of the carbohydrate stem cell marker TF1 (CD176) in ovarian cancer.
Expression of mucin 1 possessing a 3'-sulfated core1 in recurrent and metastatic breast cancer.
Highly sensitive detection of cancer antigen 15-3 using novel avian IgY antibodies.
The epitope recognized by the unique anti-MUC1 monoclonal antibody MY.1E12 involves sialyl alpha 2-3galactosyl beta 1-3N-acetylgalactosaminide linked to a distinct threonine residue in the MUC1 tandem repeat.
Modulation of MUC1 mucin as an escape mechanism of breast cancer cells from autologous cytotoxic T-lymphocytes.
Aberrant expression of MUC1 mucin in ductal hyperplasia and ductal carcinoma In situ of the breast.
Heublein S, Friese K, Kost B, Marmé F, Kuhn C, Mahner S, Dannecker C, Mayr D, Jeschke U, Vattai A
Journal of cancer research and clinical oncology 2018 Oct;144(10):1899-1907
Journal of cancer research and clinical oncology 2018 Oct;144(10):1899-1907
Cross-reactivity between MUC1 antigen and MCA: false elevation of serum CA 15-3 level in pregnant and lactating women by Ma695-Ma552-based assay.
Liang G, Fang X, Lin X, Feng X, Lu H, Wan Y, Gu Z
Breast cancer research and treatment 2018 Jun;169(2):341-347
Breast cancer research and treatment 2018 Jun;169(2):341-347
Use of CA15‑3 for screening breast cancer: An antibody‑lectin sandwich assay for detecting glycosylation of CA15‑3 in sera.
Choi JW, Moon BI, Lee JW, Kim HJ, Jin Y, Kim HJ
Oncology reports 2018 Jul;40(1):145-154
Oncology reports 2018 Jul;40(1):145-154
Inverse association of rab31 and mucin-1 (CA15-3) antigen levels in estrogen receptor-positive (ER+) breast cancer tissues with clinicopathological parameters and patients' prognosis.
Kotzsch M, Kirchner T, Soelch S, Schäfer S, Friedrich K, Baretton G, Magdolen V, Luther T
American journal of cancer research 2017;7(9):1959-1970
American journal of cancer research 2017;7(9):1959-1970
Binding of circulating anti-MUC1 antibody and serum MUC1 antigen in stage IV breast cancer.
Tang Y, Cui X, Xiao H, Qi S, Hu X, Yu Q, Shi G, Zhang X, Gu J, Yu Y, Wang L, Li Y
Molecular medicine reports 2017 May;15(5):2659-2664
Molecular medicine reports 2017 May;15(5):2659-2664
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.
Hopkinson BM, Klitgaard MC, Petersen OW, Villadsen R, Rønnov-Jessen L, Kim J
Oncotarget 2017 Feb 7;8(6):10580-10593
Oncotarget 2017 Feb 7;8(6):10580-10593
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.
Morsing M, Klitgaard MC, Jafari A, Villadsen R, Kassem M, Petersen OW, Rønnov-Jessen L
Breast cancer research : BCR 2016 Nov 3;18(1):108
Breast cancer research : BCR 2016 Nov 3;18(1):108
p53 determines prognostic significance of the carbohydrate stem cell marker TF1 (CD176) in ovarian cancer.
Heublein S, Page SK, Mayr D, Ditsch N, Jeschke U
Journal of cancer research and clinical oncology 2016 Jun;142(6):1163-70
Journal of cancer research and clinical oncology 2016 Jun;142(6):1163-70
Expression of mucin 1 possessing a 3'-sulfated core1 in recurrent and metastatic breast cancer.
Ideo H, Hinoda Y, Sakai K, Hoshi I, Yamamoto S, Oka M, Maeda K, Maeda N, Hazama S, Amano J, Yamashita K
International journal of cancer 2015 Oct 1;137(7):1652-60
International journal of cancer 2015 Oct 1;137(7):1652-60
Highly sensitive detection of cancer antigen 15-3 using novel avian IgY antibodies.
Grzywa R, Łupicka-Słowik A, Walczak M, Idzi M, Bobrek K, Boivin S, Gaweł A, Stefaniak T, Oleksyszyn J, Sieńczyk M
ALTEX 2014;31(1):43-52
ALTEX 2014;31(1):43-52
The epitope recognized by the unique anti-MUC1 monoclonal antibody MY.1E12 involves sialyl alpha 2-3galactosyl beta 1-3N-acetylgalactosaminide linked to a distinct threonine residue in the MUC1 tandem repeat.
Takeuchi H, Kato K, Denda-Nagai K, Hanisch FG, Clausen H, Irimura T
Journal of immunological methods 2002 Dec 15;270(2):199-209
Journal of immunological methods 2002 Dec 15;270(2):199-209
Modulation of MUC1 mucin as an escape mechanism of breast cancer cells from autologous cytotoxic T-lymphocytes.
Kontani K, Taguchi O, Narita T, Izawa M, Hiraiwa N, Zenita K, Takeuchi T, Murai H, Miura S, Kannagi R
British journal of cancer 2001 May 4;84(9):1258-64
British journal of cancer 2001 May 4;84(9):1258-64
Aberrant expression of MUC1 mucin in ductal hyperplasia and ductal carcinoma In situ of the breast.
Mommers EC, Leonhart AM, von Mensdorff-Pouilly S, Schol DJ, Hilgers J, Meijer CJ, Baak JP, van Diest PJ
International journal of cancer 1999 Oct 22;84(5):466-9
International journal of cancer 1999 Oct 22;84(5):466-9
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of FFPE human stomach with MUC1 antibody (clone 115D8). HIER: requires steaming of sections in 10mM citrate buffer, pH 6, for 10-20 min.
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of FFPE human breast carcinoma with MUC1 antibody (clone 115D8). HIER: requires steaming of sections in 10mM citrate buffer, pH 6, for 10-20 min.
