BS60834

antibody from Bioworld Technology, Inc
Targeting: ABHD12B BEM46L3, C14orf29
Provider product page for BS60834

Antibody data

Product number
BS60834 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ABHD12B polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human ABHD12B.
Description
The Ï«/ÉÇ hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates and different kinds of catalytic activities, yet they share the same canonical Ï«/ÉÇ hydrolase fold, which consists of an eight stranded parallel Ï«/ÉÇ structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer£ªs disease, obesity and blood clotting disorders. The Ï«/ÉÇ hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. Muta-tions in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD12 is a 398 amino acid protein that exists as 2 alternatively spliced isoforms.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ABHD12B protein structure - BS60834 shown in red.