KIF27

This gene is a member of the KIF27 (kinesin 4) sub-family of the mammalian kinesin family. The gene is an ortholog of the Drosophila Cos2 gene, which plays an important role in the Hedgehog signaling pathway. The encoded protein contains an N-terminal motor domain which includes nucleotide-binding and microtubule-interacting regions, a stalk domain containing a predicted coiled coil motif and a C-terminal tail domain. Alternatively spliced transcript variants have been observed for this gene. Pseudogenes associated with this gene are located on chromosome 9. [provided by RefSeq, Dec 2012]

Description

Kinesin family member 27

Tissue specificity

Tissue enhanced (choroid plexus, testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

9 (83834099 - 83921465)

Ensembl ID

ENSG00000165115  (ver. 103.38)

Orthologs

Mouse Kif27: ENSMUSG00000060176

UniProt

Q86VH2

neXtProt

NX_Q86VH2

Human splice variants
Mouse splice variants

Protein structure