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Protein structure
ELAC2
ElaC ribonuclease Z 2FLJ10530, HPC2
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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| LSBio |  LS-C762293 |
Polyclonal |
WB
IP
IHC
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| Novus Biologicals | NBP1-84620 |
1 references | Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 10071-1-AP |
12 references | Polyclonal |
WB
EL
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| Atlas Antibodies | HPA019535 |
2 references | Polyclonal |
WB
ICC
IHC
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| FineTest Biotech | FNab02732 |
Polyclonal |
WB
EL
ICC
IHC
|
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