Antibody data

Product number
BS60379 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Inhibin ÉÇ A polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human Inhibin ÉÇ-A.
Description
The TGFÉÇ superfamily is composed of numerous growth and differentiation factors, including transforming growth factor ÉÇ (TGFÉÇ) 1, 2 and 3; growth/differentiation factor (GDF) 1 through 8; Mullerian inhibiting substance (MIS); bone morphogenic protein (BMP) 2 through 8; glial cell line-derived neurotrophic factor (GDNF); Inhibins (Ï«, ÉÇ-A, ÉÇ-B and ÉÇ-C), Lefty and Nodal. Members of the TGFÉÇ superfamily are involved in embryonic development and adult tissue homeostasis. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins oppose the funtions of Inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue. Inhibin A, a dimer of Ï« and ÉÇ-A, and Inhibin B, a dimer of Ï« and ÉÇ-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin ÉÇ-C forms a homodimer and its expression is predominant in adult liver.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
INHBA protein structure - BS60379 shown in red.