Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60379 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Inhibin ÉÇ A polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human Inhibin ÉÇ-A.
- Description
- The TGFÉÇ superfamily is composed of numerous growth and differentiation factors, including transforming growth factor ÉÇ (TGFÉÇ) 1, 2 and 3; growth/differentiation factor (GDF) 1 through 8; Mullerian inhibiting substance (MIS); bone morphogenic protein (BMP) 2 through 8; glial cell line-derived neurotrophic factor (GDNF); Inhibins (Ï«, ÉÇ-A, ÉÇ-B and ÉÇ-C), Lefty and Nodal. Members of the TGFÉÇ superfamily are involved in embryonic development and adult tissue homeostasis. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins oppose the funtions of Inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue. Inhibin A, a dimer of Ï« and ÉÇ-A, and Inhibin B, a dimer of Ï« and ÉÇ-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin ÉÇ-C forms a homodimer and its expression is predominant in adult liver.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of Inhibin ¦Â-A pAb at 1:500 dilutionLane1:HEK293T cell lysateLane2:sp2/0 cell lysateLane3:H9C2 cell lysate