CYP2D6

gene product
CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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198 antibodies from 22 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
76 antibodies
Aviva Systems Biology
11 antibodies
Proteintech Group
2 antibodies
Novus Biologicals
7 antibodies
Abnova Corporation
7 antibodies
Abgent
2 antibodies
Atlas Antibodies
1 antibody
Biorbyt
14 antibodies
LifeSpan BioSciences, Inc.
33 antibodies
Creative Biomart
11 antibodies
Acris Antibodies GmbH
7 antibodies
RabMAbs
2 antibodies
Boster Immunoleader Biotechnology
1 antibody
Bioworld Technology, Inc
3 antibodies
GeneTex
3 antibodies
Thermo Fisher Scientific Pierce
1 antibody
Bioss
1 antibody
United States Biological
8 antibodies
Enzo Life Sciences
2 antibodies
GenWay
3 antibodies
EMD Millipore
2 antibodies
Sigma-Aldrich
1 antibody