Tissue expression
Cell line expression
Protein structure
PRICKLE1
Prickle planar cell polarity protein 1EPM1B, FLJ31937, RILP
This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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Proteintech Group | 22589-1-AP | 5 references | Polyclonal |
WB
EL
IP
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antibodies-online | ABIN1450074 | 1 references | Polyclonal |
WB
EL
ICC
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Invitrogen Antibodies | PA5-51570 | 1 references | Polyclonal |
IHC
OA |
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Boster Biological Technology | A05038 | Polyclonal |
WB
EL
ICC
|
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NovoPro Bioscience Inc. | 114190 | Polyclonal |
WB
EL
IP
|
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