DCABH-2686

antibody from Creative Diagnostics

Targeting: HNF4A HNF4, MODY, MODY1, NR2A1, TCF14

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DCABH-2686

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-2686, RRID:AB_2476576

Product name

Rabbit Anti-Human HNF4A monoclonal antibody, clone TO83-14

Antibody type

Monoclonal

Description

HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TO83-14

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.