DAPK2

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]

Description

Death associated protein kinase 2

Tissue specificity

Tissue enhanced (skeletal muscle, thyroid gland)

Subcell location

Golgi apparatus, Vesicles

Predicted location

Intracellular, Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

15 (63907036 - 64072033)

Ensembl ID

ENSG00000035664  (ver. 103.38)

Orthologs

Mouse Dapk2: ENSMUSG00000032380

UniProt

Q9UIK4

neXtProt

NX_Q9UIK4

Human splice variants
Mouse splice variants

Protein structure