BS8162

antibody from Bioworld Technology, Inc
Targeting: DPYS DHPase
Provider product page for BS8162
Western blot
Immunohistochemistry

Antibody data

Product number
BS8162 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DPYS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DPYS.
Description
DPYS (dihydropyrimidinase), also known as DHPase, Hydantoinase or DHP, is a 519 amino acid protein that is expressed in liver and kidney tissue and belongs to the DHOase family. Functioning as a homotetramer, DPYS uses zinc as a cofactor to catalyze the second step of reductive pyrimidine degradation, namely the conversion of 5,6-dihydrouracil to 3-ureidopropionate. DPYS is subject to post-translational carbamylation, an event which enhances the ability of DPYS to bind zinc ions. Defects in the gene encoding DPYS are the cause of DHP deficiency, an autosomal recessive disorder that is characterized by epileptic or convulsive attacks, dysmorphic features and severe developmental delay and congenital microvillous atrophy.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DPYS protein structure - BS8162 shown in red.