Tissue expression
Cell line expression
Protein structure
GUF1
GUF1 homolog, GTPaseFLJ13220
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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