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Protein structure
TRMT1
TRNA methyltransferase 1FLJ20244, TRM1
This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. [provided by RefSeq, May 2017]
Top validated antibodies |
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| LSBio |  LS-C832036 |
Polyclonal |
WB
EL
IHC
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| NSJ Bioreagents | RQ6689 |
Polyclonal |
WB
EL
ICC
FC
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| Proteintech Group | 14970-1-AP |
Polyclonal |
WB
EL
ICC
IHC
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| NovoPro Bioscience Inc. | 116395 |
Polyclonal |
WB
EL
ICC
IHC
|
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| Invitrogen Antibodies | 14970-1-AP |
Polyclonal |
WB
ICC
IHC
|
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