NB500-180

Uematsu K, Okumura F, Tonogai S, Joo-Okumura A, Alemayehu DH, Nishikimi A, Fukui Y, Nakatsukasa K, Kamura T
The Journal of cell biology 2016 Oct 10;215(1):95-106

DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.

Kwon HJ, Park JE, Song H, Jang CY
Journal of cell science 2016 Jul 15;129(14):2719-25

Ska1 cooperates with DDA3 for spindle dynamics and spindle attachment to kinetochore.

Park JE, Song H, Kwon HJ, Jang CY
Biochemical and biophysical research communications 2016 Feb 12;470(3):586-592

GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.

Bendre S, Rondelet A, Hall C, Schmidt N, Lin YC, Brouhard GJ, Bird AW
The Journal of cell biology 2016 Dec 5;215(5):631-647

KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte.

Chen MH, Liu Y, Wang YL, Liu R, Xu BH, Zhang F, Li FP, Xu L, Lin YH, He SW, Liao BQ, Fu XP, Wang XX, Yang XJ, Wang HL
Scientific reports 2016 Dec 19;6:39337

Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes.

Yi ZY, Ma XS, Liang QX, Zhang T, Xu ZY, Meng TG, Ouyang YC, Hou Y, Schatten H, Sun QY, Quan S
Scientific reports 2016 Dec 19;6:38574

Ras transformation uncouples the kinesin-coordinated cellular nutrient response.

Zaganjor E, Weil LM, Gonzales JX, Minna JD, Cobb MH
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10568-73

Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.

Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P
Molecular biology of the cell 2010 Mar 15;21(6):979-88

Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a.

Jang CY, Coppinger JA, Seki A, Yates JR 3rd, Fang G
Journal of cell science 2009 May 1;122(Pt 9):1334-41

DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.

Jang CY, Wong J, Coppinger JA, Seki A, Yates JR 3rd, Fang G
The Journal of cell biology 2008 Apr 21;181(2):255-67

Prophase microtubule arrays undergo flux-like behavior in mammalian cells.

Ferenz NP, Wadsworth P
Molecular biology of the cell 2007 Oct;18(10):3993-4002

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Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: Kif2a Antibody [NB500-180] - Analysis of Kif2a in Hela, 3T3 and PC12 lysate.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Simple Western: Kif2a Antibody [NB500-180] - Lane view shows a specific band for Kif2a in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.