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Western blot
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- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN152994 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Kinesin Heavy Chain Member 2A (KIF2A) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Unpurified
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.
DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.
Ska1 cooperates with DDA3 for spindle dynamics and spindle attachment to kinetochore.
GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.
KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte.
Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes.
Ras transformation uncouples the kinesin-coordinated cellular nutrient response.
Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a.
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.
Prophase microtubule arrays undergo flux-like behavior in mammalian cells.
The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK.
Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension.
Uematsu K, Okumura F, Tonogai S, Joo-Okumura A, Alemayehu DH, Nishikimi A, Fukui Y, Nakatsukasa K, Kamura T
The Journal of cell biology 2016 Oct 10;215(1):95-106
The Journal of cell biology 2016 Oct 10;215(1):95-106
DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.
Kwon HJ, Park JE, Song H, Jang CY
Journal of cell science 2016 Jul 15;129(14):2719-25
Journal of cell science 2016 Jul 15;129(14):2719-25
Ska1 cooperates with DDA3 for spindle dynamics and spindle attachment to kinetochore.
Park JE, Song H, Kwon HJ, Jang CY
Biochemical and biophysical research communications 2016 Feb 12;470(3):586-592
Biochemical and biophysical research communications 2016 Feb 12;470(3):586-592
GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.
Bendre S, Rondelet A, Hall C, Schmidt N, Lin YC, Brouhard GJ, Bird AW
The Journal of cell biology 2016 Dec 5;215(5):631-647
The Journal of cell biology 2016 Dec 5;215(5):631-647
KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte.
Chen MH, Liu Y, Wang YL, Liu R, Xu BH, Zhang F, Li FP, Xu L, Lin YH, He SW, Liao BQ, Fu XP, Wang XX, Yang XJ, Wang HL
Scientific reports 2016 Dec 19;6:39337
Scientific reports 2016 Dec 19;6:39337
Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes.
Yi ZY, Ma XS, Liang QX, Zhang T, Xu ZY, Meng TG, Ouyang YC, Hou Y, Schatten H, Sun QY, Quan S
Scientific reports 2016 Dec 19;6:38574
Scientific reports 2016 Dec 19;6:38574
Ras transformation uncouples the kinesin-coordinated cellular nutrient response.
Zaganjor E, Weil LM, Gonzales JX, Minna JD, Cobb MH
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10568-73
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10568-73
Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.
Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P
Molecular biology of the cell 2010 Mar 15;21(6):979-88
Molecular biology of the cell 2010 Mar 15;21(6):979-88
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a.
Jang CY, Coppinger JA, Seki A, Yates JR 3rd, Fang G
Journal of cell science 2009 May 1;122(Pt 9):1334-41
Journal of cell science 2009 May 1;122(Pt 9):1334-41
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.
Jang CY, Wong J, Coppinger JA, Seki A, Yates JR 3rd, Fang G
The Journal of cell biology 2008 Apr 21;181(2):255-67
The Journal of cell biology 2008 Apr 21;181(2):255-67
Prophase microtubule arrays undergo flux-like behavior in mammalian cells.
Ferenz NP, Wadsworth P
Molecular biology of the cell 2007 Oct;18(10):3993-4002
Molecular biology of the cell 2007 Oct;18(10):3993-4002
The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK.
Ganem NJ, Compton DA
The Journal of cell biology 2004 Aug 16;166(4):473-8
The Journal of cell biology 2004 Aug 16;166(4):473-8
Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension.
Homma N, Takei Y, Tanaka Y, Nakata T, Terada S, Kikkawa M, Noda Y, Hirokawa N
Cell 2003 Jul 25;114(2):229-39
Cell 2003 Jul 25;114(2):229-39
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Staining of HeLa cells fixed in 3.5% paraformaldehyde using ABIN152994 (1:5,000). Centrosome staining during interphase and spindle pole staining during mitosis.
