BS2415

antibody from Bioworld Technology, Inc
Targeting: LAMB1 CLM
Provider product page for BS2415
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS2415 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2415, RRID:AB_1663643
Product name
Laminin ÉÇ 1 (D1742) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 1711-1760 of Human Laminin ÉÇ-1.
Description
Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing type IV collagen networks, nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of Ï«, ÉÇ and ÎÛ chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble and bind to other matrix macromolecules, and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin ÎÛ-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
LAMB1 protein structure - BS2415 shown in red.