ABIN358481

antibody from antibodies-online

Targeting: GIT1

No application information provided.

Antibody Data

Product number

ABIN358481

Provider

antibodies-online

Product name

anti-GIT1 (pTyr554) antibody

Antibody type

Polyclonal

Description

Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Reactivity

Human

Host

Rabbit

Epitope

pTyr554

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Regulation of adaptor protein GIT1 in platelets, leading to the interaction between GIT1 and integrin alpha(IIb)beta3.

Sato H, Suzuki-Inoue K, Inoue O, Ozaki Y
Biochemical and biophysical research communications 2008 Mar 28;368(1):157-61

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Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK.

Stockton R, Reutershan J, Scott D, Sanders J, Ley K, Schwartz MA
Molecular biology of the cell 2007 Jun;18(6):2346-55

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Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.

Jones NP, Katan M
Molecular and cellular biology 2007 Aug;27(16):5790-805

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GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin.

Schmalzigaug R, Garron ML, Roseman JT, Xing Y, Davidson CE, Arold ST, Premont RT
Cellular signalling 2007 Aug;19(8):1733-44