Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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Validation data
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- Product number
- NBP2-29477 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal Uroplakin III Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Western Blot: Uroplakin III Antibody [NBP2-29477] - Human HEK293 lysate in the 1) absence and 2) presence of immunizing peptide using Uroplakin III antibody at 4 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.