Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11681-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11681-1-AP, RRID:AB_2160099
- Product name
- PARK7,DJ-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PARK7,DJ-1 antibody (Cat. #11681-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neuroprotective effects of polyphyllin VI against rotenone-induced toxicity in SH-SY5Y cells.
Succinylation of Park7 activates a protective metabolic response to acute kidney injury.
FKBP3 aggravates the malignant phenotype of diffuse large B-cell lymphoma by PARK7-mediated activation of Wnt/β-catenin signalling.
DJ-1 Oncogene as a Potential Diagnostic and Prognostic Biomarker for Head and Neck Cancer.
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Characterization of DJ-1, PTEN, and p-Akt as Prognostic Biomarkers in the Progression of Oral Squamous Cell Carcinoma.
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Tea Polyphenols Prevent Sepsis-Induced Lung Injury via Promoting Translocation of DJ-1 to Mitochondria.
Extracellular DJ-1 induces sterile inflammation in the ischemic brain.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Chemical proteomics reveals new targets of cysteine sulfinic acid reductase.
DJ-1 Alters Epirubicin-induced Apoptosis via Modulating Epirubicinactivated Autophagy in Human Gastric Cancer Cells.
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches.
DJ-1 knockdown inhibits growth and xenograft‑induced tumor generation of human hepatocellular carcinoma cells.
Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2.
Li L, Chen Z, Hao C
Brain research 2024 May 1;1830:148824
Brain research 2024 May 1;1830:148824
Succinylation of Park7 activates a protective metabolic response to acute kidney injury.
Pfister K, Young V, Frankel B, Silva Barbosa A, Burton J, Bons J, Zhang B, Chiba T, Uhlean R, Goetzman E, Schilling B, Sims-Lucas S
American journal of physiology. Renal physiology 2024 Jul 1;327(1):F128-F136
American journal of physiology. Renal physiology 2024 Jul 1;327(1):F128-F136
FKBP3 aggravates the malignant phenotype of diffuse large B-cell lymphoma by PARK7-mediated activation of Wnt/β-catenin signalling.
Xing X, Liu M, Wang X, Guo Q, Wang H, Wang W
Journal of cellular and molecular medicine 2024 Jan;28(1):e18041
Journal of cellular and molecular medicine 2024 Jan;28(1):e18041
DJ-1 Oncogene as a Potential Diagnostic and Prognostic Biomarker for Head and Neck Cancer.
De La Torre RA, Kerdjoudj M, Arnouk H
Cureus 2023 Mar;15(3):e36229
Cureus 2023 Mar;15(3):e36229
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Wang Y, Wang C
Cell death and differentiation 2023 Jan;30(1):125-136
Cell death and differentiation 2023 Jan;30(1):125-136
Characterization of DJ-1, PTEN, and p-Akt as Prognostic Biomarkers in the Progression of Oral Squamous Cell Carcinoma.
Kerdjoudj M, De La Torre RA, Arnouk H
Cureus 2023 Jan;15(1):e34436
Cureus 2023 Jan;15(1):e34436
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Xu Q, Cao Y, Zhong X, Qin X, Feng J, Peng H, Su Y, Ma Z, Zhou S
British journal of pharmacology 2023 Dec;180(23):3024-3044
British journal of pharmacology 2023 Dec;180(23):3024-3044
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
Tea Polyphenols Prevent Sepsis-Induced Lung Injury via Promoting Translocation of DJ-1 to Mitochondria.
Jia CM, Zhang FW, Wang SJ, Wang W, Li Y
Frontiers in cell and developmental biology 2021;9:622507
Frontiers in cell and developmental biology 2021;9:622507
Extracellular DJ-1 induces sterile inflammation in the ischemic brain.
Nakamura K, Sakai S, Tsuyama J, Nakamura A, Otani K, Kurabayashi K, Yogiashi Y, Masai H, Shichita T
PLoS biology 2021 May;19(5):e3000939
PLoS biology 2021 May;19(5):e3000939
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J
Virulence 2020 Dec;11(1):537-553
Virulence 2020 Dec;11(1):537-553
Chemical proteomics reveals new targets of cysteine sulfinic acid reductase.
Akter S, Fu L, Jung Y, Conte ML, Lawson JR, Lowther WT, Sun R, Liu K, Yang J, Carroll KS
Nature chemical biology 2018 Nov;14(11):995-1004
Nature chemical biology 2018 Nov;14(11):995-1004
DJ-1 Alters Epirubicin-induced Apoptosis via Modulating Epirubicinactivated Autophagy in Human Gastric Cancer Cells.
Pan XK, Su F, Xu LH, Yang ZS, Wang DW, Yang LJ, Kong FZ, Xie W, Feng MH
Current medical science 2018 Dec;38(6):1018-1024
Current medical science 2018 Dec;38(6):1018-1024
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
Sun R, Fu L, Liu K, Tian C, Yang Y, Tallman KA, Porter NA, Liebler DC, Yang J
Molecular & cellular proteomics : MCP 2017 Oct;16(10):1789-1800
Molecular & cellular proteomics : MCP 2017 Oct;16(10):1789-1800
Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches.
Shiau JY, Yin SY, Chang SL, Hsu YJ, Chen KW, Kuo TF, Feng CS, Yang NS, Shyur LF, Yang WC, Wen TN
Evidence-based complementary and alternative medicine : eCAM 2015;2015:475610
Evidence-based complementary and alternative medicine : eCAM 2015;2015:475610
DJ-1 knockdown inhibits growth and xenograft‑induced tumor generation of human hepatocellular carcinoma cells.
Liu S, Long G, Wei H, Shi L, Yang Z, Liu D, Hu G, Qiu H
Oncology reports 2015 Jan;33(1):201-6
Oncology reports 2015 Jan;33(1):201-6
Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2.
Björkblom B, Maple-Grødem J, Puno MR, Odell M, Larsen JP, Møller SG
Molecular and cellular biology 2014 Aug;34(16):3024-40
Molecular and cellular biology 2014 Aug;34(16):3024-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11681-1-AP(PARK7,DJ-1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PARK7,DJ-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PARK7,DJ-1. This antibody recognizes human antigen. The PARK7,DJ-1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.