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Protein structure
HSD17B4
Hydroxysteroid 17-beta dehydrogenase 4DBP, MFE-2, SDR8C1
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Top validated antibodies |
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| Proteintech Group |  15116-1-AP |
14 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | NBP2-46005 |
1 references | Monoclonal |
WB
ICC
IP
IHC
PLA
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| Invitrogen Antibodies | 15116-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| LSBio | LS-C338333 |
Monoclonal |
WB
ICC
IHC
|
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| OriGene | TA507028 |
1 references | Monoclonal |
WB
ICC
IHC
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