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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- PAB0368 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB0368, RRID:AB_1018968
- Product name
- SMAD6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SMAD6.
- Antigen sequence
RAGGPPRPMSEPGAG, NLEQRSESVRRTRSKIG- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue.
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2.
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.
Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation.
Frullanti E, Colombo F, Falvella FS, Galvan A, Noci S, De Cecco L, Incarbone M, Alloisio M, Santambrogio L, Nosotti M, Tosi D, Pastorino U, Dragani TA
International journal of cancer 2012 Sep 1;131(5):E643-8
International journal of cancer 2012 Sep 1;131(5):E643-8
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
Yoshiura S, Ohtsuka T, Takenaka Y, Nagahara H, Yoshikawa K, Kageyama R
Proceedings of the National Academy of Sciences of the United States of America 2007 Jul 3;104(27):11292-7
Proceedings of the National Academy of Sciences of the United States of America 2007 Jul 3;104(27):11292-7
Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2.
Wang Q, Wei X, Zhu T, Zhang M, Shen R, Xing L, O'Keefe RJ, Chen D
The Journal of biological chemistry 2007 Apr 6;282(14):10742-8
The Journal of biological chemistry 2007 Apr 6;282(14):10742-8
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.
Yamaguchi H, Zhu J, Yu T, Sasaki K, Umetsu H, Kidachi Y, Ryoyama K
Toxicology 2006 Sep 21;226(2-3):131-42
Toxicology 2006 Sep 21;226(2-3):131-42
Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation.
Shen R, Chen M, Wang YJ, Kaneki H, Xing L, O'keefe RJ, Chen D
The Journal of biological chemistry 2006 Feb 10;281(6):3569-76
The Journal of biological chemistry 2006 Feb 10;281(6):3569-76
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of SMAD6 in 30 ug of Jurkat cell lysate using SMAD6 polyclonal antibody (Cat # PAB0368) at 2 ug/mL .
