Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil010203040506070
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-937010203040506070
Protein structure

PDE5A

Phosphodiesterase 5A
 
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

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                        211 antibodies from 36 providers.

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                        Antibody
                        Refs
                        Type
                        WB
                        EL
                        ICC
                        IP
                        IHC
                        FC
                        Invitrogen Antibodies
                        25 antibodies
                        22624-1-APPolyclonal
                        MA5-55939Monoclonal
                        Proteintech Group
                        1 antibody
                        22624-1-AP7Polyclonal
                        Novus Biologicals
                        6 antibodies
                        H00008654-M011Monoclonal
                        H00008654-M02Monoclonal
                        Antibodies.com
                        10 antibodies
                        A53225Polyclonal
                        A54090Polyclonal
                        GeneTex
                        5 antibodies
                        GTX146721Polyclonal
                        GTX369301Polyclonal
                        NovoPro Bioscience Inc.
                        2 antibodies
                        113664Polyclonal
                        126728Polyclonal
                        St John's Laboratory
                        13 antibodies
                        STJ70656Polyclonal
                        STJ502349Polyclonal
                        Everest Biotech
                        1 antibody
                        EB06645Polyclonal
                        antibodies-online
                        49 antibodies
                        ABIN5637351Monoclonal
                        ABIN4344435Polyclonal
                        Biorbyt
                        11 antibodies
                        orb1247128Polyclonal
                        orb524709Polyclonal
                        Abnova Corporation
                        6 antibodies
                        H00008654-M011Monoclonal
                        H00008654-M02Monoclonal
                        Atlas Antibodies
                        2 antibodies
                        HPA0047292Polyclonal
                        HPA012873Polyclonal
                        Boster Biological Technology
                        2 antibodies
                        A02490-21Polyclonal
                        A02490Polyclonal
                        Enzo Life Sciences
                        1 antibody
                        ALX-210-099-C0501Polyclonal
                        OriGene
                        5 antibodies
                        AP00658SU-NPolyclonal
                        AP10239PU-NPolyclonal
                        FabGennix
                        10 antibodies
                        PD5A-101APPolyclonal
                        PPD5A-140APPolyclonal
                        Acris Antibodies GmbH
                        7 antibodies
                        AP10239PU-NPolyclonal
                        AP00658SU-NPolyclonal
                        Abbexa
                        4 antibodies
                        abx339437Polyclonal
                        abx210268Polyclonal
                        Cusabio Biotech Co., Ltd
                        2 antibodies
                        CSB-PA126186Polyclonal
                        CSB-PA132496Polyclonal
                        FineTest Biotech
                        1 antibody
                        FNab06256Polyclonal
                        NSJ Bioreagents
                        2 antibodies
                        R32652Polyclonal
                        R34720Polyclonal
                        Aviva Systems Biology
                        2 antibodies
                        ARP63250_P050Polyclonal
                        OAEB01252Polyclonal
                        Cell Signaling Technology, Inc
                        2 antibodies
                        3585Polyclonal
                        2395Polyclonal
                        Abbkine Scientific Co.Ltd.
                        1 antibody
                        ABP59864Polyclonal
                        Affinity Biosciences
                        1 antibody
                        DF9373Polyclonal
                        Bioss
                        1 antibody
                        bs-2349RPolyclonal
                        Arigo
                        1 antibody
                        ARG63726Polyclonal
                        MilliporeSigma / Merck KGaA
                        5 antibodies
                        SAB1404610Monoclonal
                        HPA004729Polyclonal
                        ProSci
                        1 antibody
                        46-153Polyclonal
                        United States Biological
                        15 antibodies
                        249920Monoclonal
                        249920-APMonoclonal
                        MyBioSource
                        4 antibodies
                        MBS420948Polyclonal
                        MBS540079Polyclonal
                        Creative Biolabs
                        5 antibodies
                        CBMAB-A6523-LYRecombinant
                        CBMAB-C1078-YYRecombinant
                        RayBiotech, Inc.
                        1 antibody
                        101-11220Monoclonal
                        Abcepta
                        1 antibody
                        AF1804aPolyclonal
                        Leading Biology
                        1 antibody
                        AMM05078GPolyclonal
                        Creative Diagnostics
                        5 antibodies
                        CABT-B10943Monoclonal
                        CABT-B10944Monoclonal