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Flow cytometry
Other assayAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 313223 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#313223, RRID:AB_2562829
- Product name
- Purified anti-human CD117 (c-kit) (MaxPar® Ready)
- Antibody type
- Monoclonal
- Antigen
- MOLM-1 megakaryocytic cell line
- Description
- CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.
- Reactivity
- Human, Bovine, Feline
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 104D2
- Vial size
- 100 µg
- Concentration
- 1 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human TF-1a erythroleukemia cells (red) and mouse EL4 T cells (blue) stained with 143Nd-anti-CD117 (104D2).
- Conjugate
- Unconjugated
