Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 313203 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#313203, RRID:AB_314982
- Product name
- PE anti-human CD117 (c-kit)
- Antibody type
- Monoclonal
- Antigen
- MOLM-1 megakaryocytic cell line
- Description
- CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemic cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.
- Reactivity
- Human, Bovine, Simian
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The CD117 antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood.
Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, Shibuya M, Yoshikawa H, Ohneda O
Blood 2007 Jul 1;110(1):151-60
Blood 2007 Jul 1;110(1):151-60
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human erythroleukemia cell line TF-1 stained with 104D2 PE
- Conjugate
- Yellow dye