Ab118223

antibody from Aladdin Scientific Corporation

Targeting: NLK

Western blot (Data presented on provider website)

Antibody Data

Product number

Ab118223

Provider

Aladdin Scientific Corporation

Product name

Recombinant NLK Antibody

Antibody type

Recombinant

Description

Rabbit anti Human NLK Antibody, Recombinant (R03-2K8), could be used for WB and so on.Application:WB: 1/500 - 1/1000 Protein FunctionRole in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity). Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.Post-translationaDually phosphorylated on Thr-303 and Tyr-305, which activates the enzyme.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 430-495


Antibody clone number

R03-2K8

Vial size

100μl,10μl,1ml,50μl

Concentration

0,5 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.