BS7852

antibody from Bioworld Technology, Inc
Targeting: GRN CLN11, PCDGF, PGRN
Provider product page for BS7852
Western blot
Immunohistochemistry

Antibody data

Product number
BS7852 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GRN polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GRN.
Description
?Acrogranin (also designated PC cell-derived growth factor (PCDGF), epithelin/granulin precursor or paragranulin) is a glycosylated protein originally purified from the highly tumorigenic, Insulin-independent mouse teratoma PC cell line. Acrogranin is a cysteine-rich molecule whose expression is essential for tumorigenicity in teratoma cells. Acrogranin is expressed in estrogen receptor-positive (ER(+)) human mammary MDA-MB-468 epithelial cells, human breast cancer MCF7 cells and human estrogen-responsive T-47D cells. Secreted acrogranin acts as an autocrine growth factor for breast carcinoma cells and overexpression may play an important role in human breast cancer. Acrogranin stimulates the growth of PC cells as well as 3T3 fibroblasts.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GRN protein structure - BS7852 shown in red.