Explore
Validate
Learn
Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- H00055323-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00055323-B01P, RRID:AB_2132691
- Product name
- Mouse Polyclonal LARP6 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. LARP6 - La ribonucleoprotein domain family, member 6,
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2.
mTORC1 phosphorylates LARP6 to stimulate type I collagen expression.
Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.
Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.
Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen.
Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA.
Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis.
Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs.
A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.
A novel role of vimentin filaments: binding and stabilization of collagen mRNAs.
Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen.
Nonmuscle myosin-dependent synthesis of type I collagen.
Slocum E, Craig A, Villanueva A, Germain D
Breast cancer research : BCR 2019 May 2;21(1):56
Breast cancer research : BCR 2019 May 2;21(1):56
mTORC1 phosphorylates LARP6 to stimulate type I collagen expression.
Zhang Y, Stefanovic B
Scientific reports 2017 Jan 23;7:41173
Scientific reports 2017 Jan 23;7:41173
Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.
Zhang Y, Stefanovic B
Scientific reports 2016 Mar 2;6:22597
Scientific reports 2016 Mar 2;6:22597
Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.
Wang H, Stefanovic B
PloS one 2014;9(10):e108870
PloS one 2014;9(10):e108870
Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen.
Stefanovic L, Longo L, Zhang Y, Stefanovic B
RNA biology 2014;11(11):1386-401
RNA biology 2014;11(11):1386-401
Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA.
Blackstock CD, Higashi Y, Sukhanov S, Shai SY, Stefanovic B, Tabony AM, Yoshida T, Delafontaine P
The Journal of biological chemistry 2014 Mar 14;289(11):7264-74
The Journal of biological chemistry 2014 Mar 14;289(11):7264-74
Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis.
Manojlovic Z, Blackmon J, Stefanovic B
PloS one 2013;8(6):e65897
PloS one 2013;8(6):e65897
Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs.
Vukmirovic M, Manojlovic Z, Stefanovic B
Molecular and cellular biology 2013 Oct;33(19):3893-906
Molecular and cellular biology 2013 Oct;33(19):3893-906
A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.
Manojlovic Z, Stefanovic B
RNA (New York, N.Y.) 2012 Feb;18(2):321-34
RNA (New York, N.Y.) 2012 Feb;18(2):321-34
A novel role of vimentin filaments: binding and stabilization of collagen mRNAs.
Challa AA, Stefanovic B
Molecular and cellular biology 2011 Sep;31(18):3773-89
Molecular and cellular biology 2011 Sep;31(18):3773-89
Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen.
Cai L, Fritz D, Stefanovic L, Stefanovic B
Journal of molecular biology 2010 Jan 15;395(2):309-26
Journal of molecular biology 2010 Jan 15;395(2):309-26
Nonmuscle myosin-dependent synthesis of type I collagen.
Cai L, Fritz D, Stefanovic L, Stefanovic B
Journal of molecular biology 2010 Aug 27;401(4):564-78
Journal of molecular biology 2010 Aug 27;401(4):564-78
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LARP6 Antibody [H00055323-B01P] - Analysis of LARP6 expression in transfected 293T cell line by LARP6 polyclonal antibody. Lane 1: LARP6 transfected lysate(54.01 KDa). Lane 2: Non-transfected lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: LARP6 Antibody [H00055323-B01P] - Analysis of purified antibody to LARP6 on HeLa cell. (antibody concentration 10 ug/ml)
