BS7942

antibody from Bioworld Technology, Inc
Targeting: FAIM2 KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2
Provider product page for BS7942
Western blot
Immunohistochemistry

Antibody data

Product number
BS7942 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FAIM2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human FAIM2.
Description
FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death. Though mechanistically related to the Fas signal, FAIM2 does not protect cells from apoptosis that is mediated by TNF-Ï« signaling. FAIM2 specifically regulates apoptosis by binding to the FAS receptor.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FAIM2 protein structure - BS7942 shown in red.