Tissue expression
Cell line expression
Protein structure
BMP7
Bone morphogenetic protein 7OP-1
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
Top validated antibodies |
|||||
Proteintech Group | ![]() |
20 references | Polyclonal |
|
|
Novus Biologicals | ![]() |
1 references | Monoclonal |
|
|
Invitrogen Antibodies | ![]() |
Polyclonal |
|
||
LSBio | ![]() |
Polyclonal |
|
||
antibodies-online | ![]() |
4 references | Polyclonal |
|