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Protein structure
KCNQ3
Potassium voltage-gated channel subfamily Q member 3EBN2, Kv7.3
This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Top validated antibodies |
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| Invitrogen Antibodies |  PA1-930 |
3 references | Polyclonal |
ICC
IHC
OA
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| GeneTex | GTX54782 |
Polyclonal |
WB
ICC
IP
IHC
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| Proteintech Group | 19966-1-AP |
2 references | Polyclonal |
WB
EL
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| antibodies-online | ABIN953015 |
4 references | Polyclonal |
WB
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| OriGene | AP55185SU-N |
Polyclonal |
WB
EL
IHC
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