Tissue expression
Cell line expression
Protein structure
SBDS
SBDS ribosome maturation factorCGI-97, FLJ10917, SDS, SWDS
This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jan 2017]
Top validated antibodies |
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Proteintech Group | ![]() |
3 references | Polyclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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