UBE2D1

gene product
E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
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115 antibodies from 21 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
antibodies-online
41 antibodies
Abnova Corporation
3 antibodies
Acris Antibodies GmbH
5 antibodies
GeneTex
3 antibodies
Novus Biologicals
5 antibodies
Thermo Fisher Scientific Pierce
2 antibodies
Abgent
2 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
13 antibodies
Bioworld Technology, Inc
1 antibody
Biorbyt
10 antibodies
RabMAbs
1 antibody
OriGene
3 antibodies
Aviva Systems Biology
2 antibodies
Creative Diagnostics
4 antibodies
Sino Biological Inc.
1 antibody
United States Biological
1 antibody
Sigma-Aldrich
3 antibodies
GenWay
1 antibody