FNab01516

antibody from FineTest Biotech

Targeting: CDC14B Cdc14B1, Cdc14B2, CDC14B3, hCDC14B

Western blot

ELISA

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Validation data

Product number: FNab01516 - Provider product page
Provider: FineTest Biotech
Product name: CDC14B antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome(APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: CDC14 cell division cycle 14 homolo g B
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CDC14B protein structure - FNab01516 shown in red.